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Publications

Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.

Dhingra P, Martinez-Fundichely A, Berger A, et al. Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. Genome Biol. 2017;18(1):141. doi:10.1186/s13059-017-1266-3

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases.

Xiong T, Meister GE, Workman RE, et al. Targeted DNA methylation in human cells using engineered dCas9-methyltransferases. Sci Rep. 2017;7(1):6732. doi:10.1038/s41598-017-06757-0

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.

Gupta RM, Hadaya J, Trehan A, et al. A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. Cell. 2017;170(3):522-533.e15. doi:10.1016/j.cell.2017.06.049

Balancing gene expression without library construction via a reusable sRNA pool.

Ghodasara A, Voigt CA. Balancing gene expression without library construction via a reusable sRNA pool. Nucleic Acids Res. 2017;45(13):8116-8127. doi:10.1093/nar/gkx530

Photoaging Mobile Apps as a Novel Opportunity for Melanoma Prevention: Pilot Study.

Brinker TJ, Schadendorf D, Klode J, et al. Photoaging Mobile Apps as a Novel Opportunity for Melanoma Prevention: Pilot Study. JMIR Mhealth Uhealth. 2017;5(7):e101. doi:10.2196/mhealth.8231

Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks.

Yeung E, Dy AJ, Martin KB, et al. Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks. Cell Syst. 2017;5(1):11-24.e12. doi:10.1016/j.cels.2017.06.001

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression.

Yu D, Khan OF, Suvà ML, et al. Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression. Proc Natl Acad Sci U S A. 2017;114(30):E6147-E6156. doi:10.1073/pnas.1701911114

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.

Zhao G, Vatanen T, Droit L, et al. Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children. Proc Natl Acad Sci U S A. 2017;114(30):E6166-E6175. doi:10.1073/pnas.1706359114

Continuous immunotypes describe human immune variation and predict diverse responses.

Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, et al. Continuous immunotypes describe human immune variation and predict diverse responses. Proc Natl Acad Sci U S A. 2017;114(30):E6097-E6106. doi:10.1073/pnas.1705065114

InDrops and Drop-seq technologies for single-cell sequencing.

Klein AM, Macosko E. InDrops and Drop-seq technologies for single-cell sequencing. Lab Chip. 2017;17(15):2540-2541. doi:10.1039/c7lc90070h