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Publications

Predicting gene expression in massively parallel reporter assays: A comparative study.

Kreimer A, Zeng H, Edwards MD, et al. Predicting gene expression in massively parallel reporter assays: A comparative study. Hum Mutat. 2017. doi:10.1002/humu.23197

Archaeogenomic evidence reveals prehistoric matrilineal dynasty.

Kennett DJ, Plog S, George RJ, et al. Archaeogenomic evidence reveals prehistoric matrilineal dynasty. Nat Commun. 2017;8:14115. doi:10.1038/ncomms14115

Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers.

Thomas C, Henry W, Cuiffo BG, et al. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Sci Signal. 2017;10(467). doi:10.1126/scisignal.aah4674

Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer.

Karnoub AE, VanHook AM. Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer. Sci Signal. 2017;10(467). doi:10.1126/scisignal.aam8855

SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity.

Ioris RM, Galié M, Ramadori G, et al. SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity. Cell Rep. 2017;18(8):1858-1868. doi:10.1016/j.celrep.2017.01.065

Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

George S, Miao D, Demetri GD, et al. Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma. Immunity. 2017;46(2):197-204. doi:10.1016/j.immuni.2017.02.001

Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment.

Gomez JE, Kaufmann-Malaga BB, Wivagg CN, et al. Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment. Elife. 2017;6. doi:10.7554/eLife.20420

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

Abelin JG, Keskin DB, Sarkizova S, et al. Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction. Immunity. 2017;46(2):315-326. doi:10.1016/j.immuni.2017.02.007

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Webb TR, Erdmann J, Stirrups KE, et al. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol. 2017;69(7):823-836. doi:10.1016/j.jacc.2016.11.056

Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.

Rothhammer V, Kenison JE, Tjon E, et al. Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation. Proc Natl Acad Sci U S A. 2017;114(8):2012-2017. doi:10.1073/pnas.1615413114