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Publications

Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states.

Kadoch C, Williams RT, Calarco JP, et al. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nat Genet. 2017;49(2):213-222. doi:10.1038/ng.3734

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.

Wang X, Lee RS, Alver BH, et al. SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation. Nat Genet. 2017;49(2):289-295. doi:10.1038/ng.3746

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.

Beyaz S, Kim JH, Pinello L, et al. The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nat Immunol. 2017;18(2):184-195. doi:10.1038/ni.3644

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.

Park RJ, Wang T, Koundakjian D, et al. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nat Genet. 2017;49(2):193-203. doi:10.1038/ng.3741

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.

Lane JM, Liang J, Vlasac I, et al. Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. Nat Genet. 2017;49(2):274-281. doi:10.1038/ng.3749

The sensitivity of exome sequencing in identifying pathogenic mutations for LGMD in the United States.

Reddy HM, Cho KA, Lek M, et al. The sensitivity of exome sequencing in identifying pathogenic mutations for LGMD in the United States. J Hum Genet. 2017;62(2):243-252. doi:10.1038/jhg.2016.116

Data Resources for Human Functional Genomics.

Ardlie KG, Guigo R. Data Resources for Human Functional Genomics. Curr Opin Syst Biol. 2017;1:75-79. doi:10.1016/j.coisb.2016.12.019

Tolerogenic dendritic cells.

Takenaka MC, Quintana FJ. Tolerogenic dendritic cells. Semin Immunopathol. 2017;39(2):113-120. doi:10.1007/s00281-016-0587-8

The Genetic Landscape of Renal Complications in Type 1 Diabetes.

Sandholm N, Van Zuydam N, Ahlqvist E, et al. The Genetic Landscape of Renal Complications in Type 1 Diabetes. J Am Soc Nephrol. 2017;28(2):557-574. doi:10.1681/ASN.2016020231

Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia.

Spracklen CN, Smith CJ, Saftlas AF, et al. Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia. Hypertens Pregnancy. 2017;36(1):30-35. doi:10.1080/10641955.2016.1223303