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Publications

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.

Zetsche B, Gootenberg JS, Abudayyeh OO, et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell. 2015;163(3):759-71. doi:10.1016/j.cell.2015.09.038

The transcriptional landscape of age in human peripheral blood.

Peters MJ, Joehanes R, Pilling LC, et al. The transcriptional landscape of age in human peripheral blood. Nat Commun. 2015;6:8570. doi:10.1038/ncomms9570

Oncogenic Signaling Adaptor Proteins.

Luo LY, Hahn WC. Oncogenic Signaling Adaptor Proteins. J Genet Genomics. 2015;42(10):521-9. doi:10.1016/j.jgg.2015.09.001

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.

Kogelman LJA, Zhernakova DV, Westra HJ, et al. An integrative systems genetics approach reveals potential causal genes and pathways related to obesity. Genome Med. 2015;7:105. doi:10.1186/s13073-015-0229-0

Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.

Kugel S, Feldman JL, Klein MA, et al. Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer. Cell Rep. 2015;13(3):479-88. doi:10.1016/j.celrep.2015.09.022

A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling.

Patterson HC, Gerbeth C, Thiru P, et al. A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. Proc Natl Acad Sci U S A. 2015;112(42):E5679-88. doi:10.1073/pnas.1517932112

Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi.

Assefa S, Lim C, Preston MD, et al. Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi. Proc Natl Acad Sci U S A. 2015;112(42):13027-32. doi:10.1073/pnas.1509534112

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.

Cao Z, Conway KL, Heath RJ, et al. Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity. 2015;43(4):715-26. doi:10.1016/j.immuni.2015.10.005

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.

Kim HJ, Barnitz A, Kreslavsky T, et al. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios. Science. 2015;350(6258):334-9. doi:10.1126/science.aad0616

Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise.

Kim J, Akbani R, Creighton CJ, et al. Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise. Clin Cancer Res. 2015;21(20):4514-24. doi:10.1158/1078-0432.CCR-14-1215