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Publications

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.

Gan W, Dai X, Lunardi A, et al. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Mol Cell. 2015;59(6):917-30. doi:10.1016/j.molcel.2015.07.026

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Hiraki M, Hwang SY, Cao S, et al. Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis. Chem Biol. 2015;22(9):1206-16. doi:10.1016/j.chembiol.2015.07.016

De novo mutations in ARID1B associated with both syndromic and non-syndromic short stature.

Yu Y, Yao R, Wang L, et al. De novo mutations in ARID1B associated with both syndromic and non-syndromic short stature. BMC Genomics. 2015;16:701. doi:10.1186/s12864-015-1898-1

Host genetic variation impacts microbiome composition across human body sites.

Blekhman R, Goodrich JK, Huang K, et al. Host genetic variation impacts microbiome composition across human body sites. Genome Biol. 2015;16:191. doi:10.1186/s13059-015-0759-1

Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.

Pelleau S, Moss EL, Dhingra SK, et al. Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt. Proc Natl Acad Sci U S A. 2015;112(37):11672-7. doi:10.1073/pnas.1507142112

Likelihood-based complex trait association testing for arbitrary depth sequencing data.

Yan S, Yuan S, Xu Z, et al. Likelihood-based complex trait association testing for arbitrary depth sequencing data. Bioinformatics. 2015;31(18):2955-62. doi:10.1093/bioinformatics/btv307

Global diversity, population stratification, and selection of human copy-number variation.

Sudmant PH, Mallick S, Nelson BJ, et al. Global diversity, population stratification, and selection of human copy-number variation. Science. 2015;349(6253):aab3761. doi:10.1126/science.aab3761

Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival.

Johnston AJ, Murphy KT, Jenkinson L, et al. Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival. Cell. 2015;162(6):1365-78. doi:10.1016/j.cell.2015.08.031

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.

Avraham R, Haseley N, Brown D, et al. Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses. Cell. 2015;162(6):1309-21. doi:10.1016/j.cell.2015.08.027

Output File Formats

Whittaker S, Cowley G, Wagner S, Root D, Garraway L. Output File Formats. Molecular cancer therapeutics. 2015. doi:10.1158/1535-7163.MCT-15-0136-T