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Publications

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function.

Chun E, Lavoie S, Michaud M, et al. CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function. Cell Rep. 2015;12(2):244-57. doi:10.1016/j.celrep.2015.06.024

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.

Basarab GS, Kern GH, McNulty J, et al. Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases. Sci Rep. 2015;5:11827. doi:10.1038/srep11827

Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.

Wu SC, Li LS, Kopp N, et al. Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2015;28(1):29-41. doi:10.1016/j.ccell.2015.06.005

Data analysis: Create a cloud commons.

Stein LD, Knoppers BM, Campbell P, Getz G, Korbel JO. Data analysis: Create a cloud commons. Nature. 2015;523(7559):149-51. doi:10.1038/523149a

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

Krönke J, Fink EC, Hollenbach PW, et al. Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. Nature. 2015;523(7559):183-8. doi:10.1038/nature14610

Cross-sectional examination of metabolites and metabolic phenotypes in uremia.

Kalim S, Clish CB, Deferio JJ, et al. Cross-sectional examination of metabolites and metabolic phenotypes in uremia. BMC Nephrol. 2015;16:98. doi:10.1186/s12882-015-0100-y

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.

Rickman KA, Lach FP, Abhyankar A, et al. Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia. Cell Rep. 2015;12(1):35-41. doi:10.1016/j.celrep.2015.06.014

Antibiotic efficacy is linked to bacterial cellular respiration.

Lobritz MA, Belenky P, Porter CBM, et al. Antibiotic efficacy is linked to bacterial cellular respiration. Proc Natl Acad Sci U S A. 2015;112(27):8173-80. doi:10.1073/pnas.1509743112

Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.

Jarvis TC, Davies DR, Hisaminato A, et al. Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure. 2015;23(7):1293-304. doi:10.1016/j.str.2015.03.027

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.

Trynka G, Westra HJ, Slowikowski K, et al. Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci. Am J Hum Genet. 2015;97(1):139-52. doi:10.1016/j.ajhg.2015.05.016