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Publications

Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen.

Stomper J, Niroula A, Belizaire R, McConkey M, Bandaru TS, Ebert BL. Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen. Cell reports. 2025;44(4):115494. doi:10.1016/j.celrep.2025.115494

CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution.

Dinh KN, Vázquez-García I, Chan A, et al. CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution. PLoS computational biology. 2025;21(4):e1012902. doi:10.1371/journal.pcbi.1012902

Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes.

Martin-Rufino JD, Caulier A, Lee S, et al. Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes. Science (New York, N.Y.). 2025;388(6742):52-59. doi:10.1126/science.ads7951

Lipotoxicity Induces Beta Cell Small Extracellular Vesicle-mediated β-cell Dysfunction in Male Mice.

Roy A, Hoff A, Her TK, et al. Lipotoxicity Induces Beta Cell Small Extracellular Vesicle-mediated β-cell Dysfunction in Male Mice. Endocrinology. 2025. doi:10.1210/endocr/bqaf067

Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies.

Chalitsios C V, Markozannes G, Papagiannopoulos C, et al. Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2025;34(4):568-577. doi:10.1158/1055-9965.EPI-24-1534

Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care.

Kreienkamp RJ, Deutsch AJ, Huerta-Chagoya A, et al. Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.03.06.25323229

Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection.

Perugino CA, Liu H, Feldman J, et al. Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection. Cell reports. 2025;44(4):115472. doi:10.1016/j.celrep.2025.115472

New Threshold for Defining Mild Aortic Stenosis Derived From Velocity-Encoded MRI in 60,000 Individuals.

Kany S, Rämö JT, Playford D, et al. New Threshold for Defining Mild Aortic Stenosis Derived From Velocity-Encoded MRI in 60,000 Individuals. Journal of the American College of Cardiology. 2025;85(13):1387-1399. doi:10.1016/j.jacc.2025.01.035

Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance.

Waterbury AL, Caroli J, Zhang O, et al. Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. Nature communications. 2025;16(1):3156. doi:10.1038/s41467-025-57477-3

Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target.

Schuermans A, Honigberg MC. Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target. Nature reviews. Cardiology. 2025. doi:10.1038/s41569-025-01148-9