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Publications

Design of a potent interleukin-21 mimic for cancer immunotherapy.

Chun JH, Lim BS, Roy S, et al. Design of a potent interleukin-21 mimic for cancer immunotherapy. Science immunology. 2025;10(111):eadx1582. doi:10.1126/sciimmunol.adx1582

Effects of an app-based brief gratitude practice on positive and negative daily affect during the COVID-19 pandemic.

Lin S, Shen S, Ivcevic Z, et al. Effects of an app-based brief gratitude practice on positive and negative daily affect during the COVID-19 pandemic. Acta psychologica. 2025;260:105579. doi:10.1016/j.actpsy.2025.105579

Estimating disorder probability based on polygenic prediction using the BPC approach.

Uffelmann E, Price AL, Posthuma D, Peyrot WJ, , . Estimating disorder probability based on polygenic prediction using the BPC approach. Nature communications. 2025;16(1):8443. doi:10.1038/s41467-025-62929-x

InfEHR: Clinical phenotype resolution through deep geometric learning on electronic health records.

Kauffman J, Holmes E, Vaid A, et al. InfEHR: Clinical phenotype resolution through deep geometric learning on electronic health records. Nature communications. 2025;16(1):8475. doi:10.1038/s41467-025-63366-6

Single-cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathway.

Juric I, Fink EE, Qiu H, et al. Single-cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathway. NPJ precision oncology. 2025;9(1):318. doi:10.1038/s41698-025-01093-3

A clinical milestone for CRISPR in sickle-cell disease.

Mboowa G. A clinical milestone for CRISPR in sickle-cell disease. Nature reviews. Genetics. 2025. doi:10.1038/s41576-025-00898-z

Genomic Analysis of Cardiovascular Diseases Utilizing Space Omics and Medical Atlas.

Lee R, Rayhun A, Kim JK, et al. Genomic Analysis of Cardiovascular Diseases Utilizing Space Omics and Medical Atlas. Genes. 2025;16(9). doi:10.3390/genes16090996

PKSmart: an open-source computational model to predict intravenous pharmacokinetics of small molecules.

Seal S, Trapotsi MA, Mahale M, et al. PKSmart: an open-source computational model to predict intravenous pharmacokinetics of small molecules. Journal of cheminformatics. 2025;17(1):147. doi:10.1186/s13321-025-01066-5

In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas.

Jürgensen L, Benfatto S, Schmid S, et al. In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas. Acta neuropathologica. 2025;150(1):34. doi:10.1007/s00401-025-02939-7

Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS).

Fischer GM, Fang R, Xu S, et al. Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS). The British journal of dermatology. 2025. doi:10.1093/bjd/ljaf378