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Publications

Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases.

Yin Z, Klionsky DJ. Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases. Autophagy. 2024:1-2. doi:10.1080/15548627.2024.2323294

Graph Fourier transform for spatial omics representation and analyses of complex organs.

Chang Y, Liu J, Jiang Y, et al. Graph Fourier transform for spatial omics representation and analyses of complex organs. Research square. 2024. doi:10.21203/rs.3.rs-3952048/v1

Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects.

Broberg M, Ampuja M, Jones S, et al. Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects. BMC genomics. 2024;25(1):256. doi:10.1186/s12864-024-10172-x

Magnetic Resonance Imaging-based Prostate Cancer Screening in Carriers of Pathogenic Germline Mutations: Interim Results from the Initial Screening Round of the Prostate Cancer Genetic Risk Evaluation and Screening Study.

Amini AE, Hunter AE, Almashad A, et al. Magnetic Resonance Imaging-based Prostate Cancer Screening in Carriers of Pathogenic Germline Mutations: Interim Results from the Initial Screening Round of the Prostate Cancer Genetic Risk Evaluation and Screening Study. European urology oncology. 2024. doi:10.1016/j.euo.2024.01.015

Epigenetic profiling reveals key genes and cis-regulatory networks specific to human parathyroids.

Jung YL, Zhao W, Li I, et al. Epigenetic profiling reveals key genes and cis-regulatory networks specific to human parathyroids. Nature communications. 2024;15(1):2106. doi:10.1038/s41467-024-46181-3

Cas9-assisted biological containment of a genetically engineered human commensal bacterium and genetic elements.

Hayashi N, Lai Y, Fuerte-Stone J, Mimee M, Lu TK. Cas9-assisted biological containment of a genetically engineered human commensal bacterium and genetic elements. Nature communications. 2024;15(1):2096. doi:10.1038/s41467-024-45893-w

MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch.

Jakobsen ST, Jensen RAM, Madsen MS, et al. MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch. Nature genetics. 2024. doi:10.1038/s41588-024-01676-z

Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation.

Kim KL, Rahme GJ, Goel VY, Farran CAE, Hansen AS, Bernstein BE. Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation. Molecular cell. 2024. doi:10.1016/j.molcel.2024.02.007

A multi-ancestry genome-wide association study in type 1 diabetes.

Michalek DA, Tern C, Zhou W, et al. A multi-ancestry genome-wide association study in type 1 diabetes. Human molecular genetics. 2024. doi:10.1093/hmg/ddae024

Mechanism for feature learning in neural networks and backpropagation-free machine learning models.

Radhakrishnan A, Beaglehole D, Pandit P, Belkin M. Mechanism for feature learning in neural networks and backpropagation-free machine learning models. Science (New York, N.Y.). 2024. doi:10.1126/science.adi5639