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Publications

New opportunities to overcome T cell dysfunction: the role of transcription factors and how to target them.

Wu B, Koehler AN, Westcott PMK. New opportunities to overcome T cell dysfunction: the role of transcription factors and how to target them. Trends in biochemical sciences. 2024. doi:10.1016/j.tibs.2024.08.002

Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy.

DeForest N, Wang Y, Zhu Z, et al. Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy. Nature communications. 2024;15(1):8068. doi:10.1038/s41467-024-52105-y

Sequence variants influencing the regulation of serum IgG subclass levels.

Olafsdottir TA, Thorleifsson G, Portilla AL de L, et al. Sequence variants influencing the regulation of serum IgG subclass levels. Nature communications. 2024;15(1):8054. doi:10.1038/s41467-024-52470-8

Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans.

Chen JH, Elmelech L, Tang AL, Hacohen N. Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans. Current opinion in immunology. 2024;91:102463. doi:10.1016/j.coi.2024.102463

Spatial omics advances for in situ RNA biology.

Ren J, Luo S, Shi H, Wang X. Spatial omics advances for in situ RNA biology. Molecular cell. 2024. doi:10.1016/j.molcel.2024.08.002

Semi-supervised machine learning method for predicting homogeneous ancestry groups to assess Hardy-Weinberg equilibrium in diverse whole-genome sequencing studies.

Shyr D, Dey R, Li X, et al. Semi-supervised machine learning method for predicting homogeneous ancestry groups to assess Hardy-Weinberg equilibrium in diverse whole-genome sequencing studies. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.08.018

Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer.

Liu Y, Peng C, Brorson IS, et al. Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.08.009

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.

Greensmith R, Lape IT, Riella C V, et al. CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment. EMBO molecular medicine. 2024. doi:10.1038/s44321-024-00126-x

Postoperative Organ Dysfunction Risk Stratification Using Extracellular Vesicle-Derived circRNAs in Pediatric Congenital Heart Surgery.

Alhamdan F, Yuki K. Postoperative Organ Dysfunction Risk Stratification Using Extracellular Vesicle-Derived circRNAs in Pediatric Congenital Heart Surgery. Cells. 2024;13(17). doi:10.3390/cells13171417

Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults-Associations with Frailty and Cardiometabolic Conditions.

Clayton-Chubb D, Vaughan N V, George ES, et al. Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults-Associations with Frailty and Cardiometabolic Conditions. Nutrients. 2024;16(17). doi:10.3390/nu16172978