ӳ��ý

Publications

XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells.

Zou T, Zhou M, Gupta A, et al. XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells. Cell reports. 2024;43(2):113600. doi:10.1016/j.celrep.2023.113600

BCFtools/liftover: an accurate and comprehensive tool to convert genetic variants across genome assemblies.

Genovese G, Rockweiler NB, Gorman BR, et al. BCFtools/liftover: an accurate and comprehensive tool to convert genetic variants across genome assemblies. Bioinformatics (Oxford, England). 2024. doi:10.1093/bioinformatics/btae038

Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity.

Horne RI, Wilson-Godber J, Díaz AG, et al. Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity. Journal of chemical information and modeling. 2024. doi:10.1021/acs.jcim.3c01777

Mendelian Randomization Applied to Neurology.

Gagnon E, Daghlas I, Zagkos L, et al. Mendelian Randomization Applied to Neurology. Neurology. 2024;102(4):e209128. doi:10.1212/WNL.0000000000209128

Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade.

Wang C, Chen L, Fu D, et al. Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade. Clinical & experimental metastasis. 2024. doi:10.1007/s10585-023-10257-z

Narrowing the Diagnostic Gap: Genomes, Episignatures, Long-Read Sequencing and Health Economic Analyses in an Exome-Negative Intellectual Disability Cohort.

Dias KR, Shrestha R, Schofield D, et al. Narrowing the Diagnostic Gap: Genomes, Episignatures, Long-Read Sequencing and Health Economic Analyses in an Exome-Negative Intellectual Disability Cohort. Genetics in medicine : official journal of the American College of Medical Genetics. 2024:101076. doi:10.1016/j.gim.2024.101076

Deciphering cell states and genealogies of human hematopoiesis.

Weng C, Yu F, Yang D, et al. Deciphering cell states and genealogies of human hematopoiesis. Nature. 2024. doi:10.1038/s41586-024-07066-z

Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study.

Windred DP, Burns AC, Lane JM, et al. Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study. Sleep. 2024;47(1). doi:10.1093/sleep/zsad253

Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma.

Wu Q, Ellis H, Siravegna G, et al. Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024;30(1):198-208. doi:10.1158/1078-0432.CCR-23-1317

Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes.

Pathak GA, Singh K, Choi KW, et al. Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes. JAMA psychiatry. 2024;81(1):34-44. doi:10.1001/jamapsychiatry.2023.4127