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Publications

Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.

Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.07.548101

S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness.

Yurkovetskiy L, Egri S, Kurhade C, et al. S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.30.535005

Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis.

Akshay A, Katoch M, Shekarchizadeh N, et al. Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.04.546825

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases.

Truong B, Hull LE, Ruan Y, et al. Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.02.21.23286110

Structurally divergent and recurrently mutated regions of primate genomes.

Mao Y, Harvey WT, Porubsky D, et al. Structurally divergent and recurrently mutated regions of primate genomes. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.07.531415

Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion.

Reedy JL, Crossen AJ, Ward RA, et al. Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.28.534632

Contextualizing protein representations using deep learning on protein networks and single-cell data.

Li MM, Huang Y, Sumathipala M, et al. Contextualizing protein representations using deep learning on protein networks and single-cell data. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.18.549602

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.

Lee DSM, Cardone KM, Zhang DY, et al. Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.07.16.23292724

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.

Lee DSM, Cardone KM, Zhang DY, et al. Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.07.16.23292724

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Yuan K, Longchamps RJ, Pardiñas AF, et al. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.01.07.23284293