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Publications

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.

Ottensmann L, Tabassum R, Ruotsalainen SE, et al. Genome-wide association analysis of plasma lipidome identifies 495 genetic associations. Nature communications. 2023;14(1):6934. doi:10.1038/s41467-023-42532-8

ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy.

Wang M, Ran X, Leung W, et al. ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy. Genes & development. 2023;37(19-20):929-943. doi:10.1101/gad.351084.123

Decoding Genetics, Ancestry, and Geospatial Context for Precision Health.

Koyama S, Wang Y, Paruchuri K, et al. Decoding Genetics, Ancestry, and Geospatial Context for Precision Health. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.10.24.23297096

Protein Language Models Uncover Carbohydrate-Active Enzyme Function in Metagenomics.

Thurimella K, Mohamed AMT, Graham DB, et al. Protein Language Models Uncover Carbohydrate-Active Enzyme Function in Metagenomics. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.23.563620

High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics.

Sept CE, Tak E, Cerda-Smith CG, et al. High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.20.563340

Allostatic load in early adolescence: gene / environment contributions and relevance for mental health.

Hoffman KW, Tran KT, Moore TM, et al. Allostatic load in early adolescence: gene / environment contributions and relevance for mental health. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.10.27.23297674

affinity maturation of murine B cells reprogrammed to express human antibodies.

Yin Y, Guo Y, Jiang Y, et al. affinity maturation of murine B cells reprogrammed to express human antibodies. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.20.563154

Modular vector assembly enables rapid assessment of emerging CRISPR technologies.

McGee A V, Liu Y V, Griffith AL, et al. Modular vector assembly enables rapid assessment of emerging CRISPR technologies. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.25.564061

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.

Miller TE, Farran CAE, Couturier CP, et al. Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.24.563466

A multidimensional analysis reveals distinct immune phenotypes and tertiary lymphoid structure-like aggregates in the bone marrow of pediatric acute myeloid leukemia.

Koedijk JB, van der Werf I, Penter L, et al. A multidimensional analysis reveals distinct immune phenotypes and tertiary lymphoid structure-like aggregates in the bone marrow of pediatric acute myeloid leukemia. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.03.03.23286485