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Publications

Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs.

Lingaas F, Tengvall K, Jansen JH, et al. Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs. PLoS genetics. 2023;19(1):e1010599. doi:10.1371/journal.pgen.1010599

Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening.

Tan J, Shenker-Tauris N, Rodriguez-Hernaez J, et al. Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening. Nature biotechnology. 2023. doi:10.1038/s41587-022-01612-8

Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

ӳ��ýaway A, Yin X, Williamson A, et al. Loci for insulin processing and secretion provide insight into type 2 diabetes risk. American journal of human genetics. 2023;110(2):284-299. doi:10.1016/j.ajhg.2023.01.002

Robust single-cell matching and multimodal analysis using shared and distinct features.

Zhu B, Chen S, Bai Y, et al. Robust single-cell matching and multimodal analysis using shared and distinct features. Nature methods. 2023;20(2):304-315. doi:10.1038/s41592-022-01709-7

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.

Rajagopal VM, Ganna A, Coleman JRI, et al. Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity. Scientific reports. 2023;13(1):429. doi:10.1038/s41598-022-26845-0

Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.

Parry EM, Leshchiner I, Guièze R, et al. Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine. 2023;29(1):158-169. doi:10.1038/s41591-022-02113-6

Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury.

Stein MB, Jain S, Parodi L, et al. Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury. Translational psychiatry. 2023;13(1):24. doi:10.1038/s41398-023-02313-9

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.

Wang Y, Fan JL, Melms JC, et al. Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens. Nature genetics. 2023;55(1):19-25. doi:10.1038/s41588-022-01268-9

Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume.

Aquilanti E, Kageler L, Watson J, et al. Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume. Neuro-oncology. 2023. doi:10.1093/neuonc/noad024

Biliary epithelial cells are facultative liver stem cells during liver regeneration in adult zebrafish.

Oderberg IM, Goessling W. Biliary epithelial cells are facultative liver stem cells during liver regeneration in adult zebrafish. JCI insight. 2023;8(1). doi:10.1172/jci.insight.163929