Huang TP, Zhao KT, Miller SM, et al. Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors. Nat Biotechnol. 2019. doi:10.1038/s41587-019-0134-y
Publications
Struntz NB, Chen A, Deutzmann A, et al. Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chem Biol. 2019;26(5):711-723.e14. doi:10.1016/j.chembiol.2019.02.009
Price C, Gill S, Ho ZV, et al. Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers. Cancer Res. 2019;79(10):2564-2579. doi:10.1158/0008-5472.CAN-18-2674
Maianti JP, Tan GA, Vetere A, et al. Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nat Chem Biol. 2019. doi:10.1038/s41589-019-0271-0
Chan MM, Smith ZD, Grosswendt S, et al. Molecular recording of mammalian embryogenesis. Nature. 2019. doi:10.1038/s41586-019-1184-5
Brown EM, Ke X, Hitchcock D, et al. Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis. Cell Host Microbe. 2019;25(5):668-680.e7. doi:10.1016/j.chom.2019.04.002
Ghandi M, Huang FW, Jané-Valbuena J, et al. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature. 2019. doi:10.1038/s41586-019-1186-3
Rohban MH, Abbasi HS, Singh S, Carpenter AE. Capturing single-cell heterogeneity via data fusion improves image-based profiling. Nat Commun. 2019;10(1):2082. doi:10.1038/s41467-019-10154-8
Zhang F, Wei K, Slowikowski K, et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nat Immunol. 2019. doi:10.1038/s41590-019-0378-1
Cohen KA, Manson AL, Abeel T, et al. Extensive global movement of multidrug-resistant strains revealed by whole-genome analysis. Thorax. 2019. doi:10.1136/thoraxjnl-2018-211616