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Publications

Rapid evolution of a skin-lightening allele in southern African KhoeSan.

Lin M, Siford RL, Martin AR, et al. Rapid evolution of a skin-lightening allele in southern African KhoeSan. Proc Natl Acad Sci U S A. 2018;115(52):13324-13329. doi:10.1073/pnas.1801948115

Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.

Ron-Harel N, Notarangelo G, Ghergurovich JM, et al. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018;115(52):13347-13352. doi:10.1073/pnas.1804149115

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.

Gannon HS, Zou T, Kiessling MK, et al. Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nat Commun. 2018;9(1):5450. doi:10.1038/s41467-018-07824-4

Genomic evolution of cancer models: perils and opportunities.

Ben-David U, Beroukhim R, Golub TR. Genomic evolution of cancer models: perils and opportunities. Nat Rev Cancer. 2018. doi:10.1038/s41568-018-0095-3

Atom- and Step-Economical Ruthenium-Catalyzed Synthesis of Esters from Aldehydes or Ketones and Carboxylic Acids.

Runikhina SA, Usanov DL, Chizhov AO, Chusov D. Atom- and Step-Economical Ruthenium-Catalyzed Synthesis of Esters from Aldehydes or Ketones and Carboxylic Acids. Org Lett. 2018;20(24):7856-7859. doi:10.1021/acs.orglett.8b03375

Structures and gating mechanism of human TRPM2.

Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science. 2018;362(6421). doi:10.1126/science.aav4809

Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures.

Mortison JD, Schenone M, Myers JA, et al. Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures. Cell Chem Biol. 2018;25(12):1506-1518.e13. doi:10.1016/j.chembiol.2018.09.010

Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.

Marian CA, Stoszko M, Wang L, et al. Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal. Cell Chem Biol. 2018;25(12):1443-1455.e14. doi:10.1016/j.chembiol.2018.08.004

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.

Dejanovic B, Huntley MA, De Mazière A, et al. Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies. Neuron. 2018;100(6):1322-1336.e7. doi:10.1016/j.neuron.2018.10.014

High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human.

Wang X, He L, Goggin SM, et al. High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human. Nat Commun. 2018;9(1):5380. doi:10.1038/s41467-018-07746-1