ӳ��ý

Gene Regulation Observatory

Monogenic and Polygenic Contributions to QTc Prolongation in the Population.

Nauffal V, Morrill VN, Jurgens SJ, et al. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. 2022;145(20):1524-1533. doi:10.1161/CIRCULATIONAHA.121.057261

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.

Halford JL, Morrill VN, Choi SH, et al. Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nature communications. 2022;13(1):5767. doi:10.1038/s41467-022-33534-z

Functional inference of gene regulation using single-cell multi-omics.

Kartha V, Duarte F, Hu Y, et al. Functional inference of gene regulation using single-cell multi-omics. Cell genomics. 2022;2(9). doi:10.1016/j.xgen.2022.100166

Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.

Uzquiano A, Kedaigle AJ, Pigoni M, et al. Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022;185(20):3770-3788.e27. doi:10.1016/j.cell.2022.09.010

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues.

Zhao T, Chiang ZD, Morriss JW, et al. Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. Nature. 2022;601(7891):85-91. doi:10.1038/s41586-021-04217-4