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Stanley Center for Psychiatric Research

Traumatic stress and accelerated DNA methylation age: A meta-analysis.

Wolf EJ, Maniates H, Nugent N, et al. Traumatic stress and accelerated DNA methylation age: A meta-analysis. Psychoneuroendocrinology. 2018;92:123-134. doi:10.1016/j.psyneuen.2017.12.007

Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells.

Giera S, Luo R, Ying Y, et al. Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells. Elife. 2018;7. doi:10.7554/eLife.33385

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission.

Nehme R, Zuccaro E, Ghosh SD, et al. Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Rep. 2018;23(8):2509-2523. doi:10.1016/j.celrep.2018.04.066

The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress.

Zelikowsky M, Hui M, Karigo T, et al. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 2018;173(5):1265-1279.e19. doi:10.1016/j.cell.2018.03.037

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.

Gormley P, Kurki MI, Hiekkala ME, et al. Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families. Neuron. 2018;98(4):743-753.e4. doi:10.1016/j.neuron.2018.04.014

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.

Martin AR, Karczewski KJ, Kerminen S, et al. Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland. Am J Hum Genet. 2018;102(5):760-775. doi:10.1016/j.ajhg.2018.03.003

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

Evans LM, Tahmasbi R, Vrieze SI, et al. Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits. Nat Genet. 2018;50(5):737-745. doi:10.1038/s41588-018-0108-x

Distinguishing postpartum and antepartum depressive trajectories in a large population-based cohort: the impact of exposure to adversity and offspring gender.

Denckla CA, Mancini AD, Consedine NS, et al. Distinguishing postpartum and antepartum depressive trajectories in a large population-based cohort: the impact of exposure to adversity and offspring gender. Psychol Med. 2018;48(7):1139-1147. doi:10.1017/S0033291717002549

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Huckins LM, Hatzikotoulas K, Southam L, et al. Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Mol Psychiatry. 2018;23(5):1169-1180. doi:10.1038/mp.2017.88

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.

Verbanck M, Chen CY, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(5):693-698. doi:10.1038/s41588-018-0099-7