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Eric Lander

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.

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Mikkelsen T, Wakefield M, Aken B, et al. Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature. 2007;447(7141):167-77. doi:10.1038/nature05805.

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.

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Xie X, Mikkelsen TS, Gnirke A, Lindblad-Toh K, Kellis M, Lander ES. Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proc Natl Acad Sci U S A. 2007;104(17):7145-50. doi:10.1073/pnas.0701811104.

A second major histocompatibility complex susceptibility locus for multiple sclerosis.

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Yeo TW, De Jager PL, Gregory SG, et al. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol. 2007;61(3):228-36. doi:10.1002/ana.21063.

The mammalian epigenome.

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Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 2007;128(4):669-81. doi:10.1016/j.cell.2007.01.033.

Sleep-related epilepsy in the A/J mouse.

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Strohl K, Gallaugher L, Lynn A, et al. Sleep-related epilepsy in the A/J mouse. Sleep. 2007;30(2):169-76.

A genome-wide map of diversity in Plasmodium falciparum.

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Volkman SK, Sabeti PC, DeCaprio D, et al. A genome-wide map of diversity in Plasmodium falciparum. Nat Genet. 2007;39(1):113-9. doi:10.1038/ng1930.

A second fatty acid amide hydrolase with variable distribution among placental mammals.

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Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF. A second fatty acid amide hydrolase with variable distribution among placental mammals. J Biol Chem. 2006;281(48):36569-78. doi:10.1074/jbc.M606646200.

Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida.

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Bourlat SJ, Juliusdottir T, Lowe CJ, et al. Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida. Nature. 2006;444(7115):85-8. doi:10.1038/nature05241.

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

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Lamb J, Crawford ED, Peck D, et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science. 2006;313(5795):1929-35. doi:10.1126/science.1132939.

Genome-scale loss-of-function screening with a lentiviral RNAi library.

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Root DE, Hacohen N, Hahn WC, Lander ES, Sabatini DM. Genome-scale loss-of-function screening with a lentiviral RNAi library. Nat Methods. 2006;3(9):715-9. doi:10.1038/nmeth924.