Publications

Mixed-effects association of single cells identifies an expanded effector CD4 T cell subset in rheumatoid arthritis.

Fonseka CY, Rao DA, Teslovich NC, et al. Mixed-effects association of single cells identifies an expanded effector CD4 T cell subset in rheumatoid arthritis. Sci Transl Med. 2018;10(463). doi:10.1126/scitranslmed.aaq0305

Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation.

Ahlberg G, Refsgaard L, Lundegaard PR, et al. Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation. Nat Commun. 2018;9(1):4316. doi:10.1038/s41467-018-06618-y

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1.

Harmand TJ, Bousbaine D, Chan A, et al. One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1. Bioconjug Chem. 2018;29(10):3245-3249. doi:10.1021/acs.bioconjchem.8b00563

Phenome-wide association studies across large population cohorts support drug target validation.

Diogo D, Tian C, Franklin CS, et al. Phenome-wide association studies across large population cohorts support drug target validation. Nat Commun. 2018;9(1):4285. doi:10.1038/s41467-018-06540-3

Polygenic Risk Scoring for Coronary Heart Disease: The First Risk Factor.

Natarajan P. Polygenic Risk Scoring for Coronary Heart Disease: The First Risk Factor. J Am Coll Cardiol. 2018;72(16):1894-1897. doi:10.1016/j.jacc.2018.08.1041

Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland.

Strausz S, Havulinna AS, Tuomi T, et al. Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland. BMJ Open. 2018;8(10):e022752. doi:10.1136/bmjopen-2018-022752

Late-Onset Crohn's Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics.

Li D, Haritunians T, Landers C, et al. Late-Onset Crohn’s Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics. Inflamm Bowel Dis. 2018;24(11):2413-2422. doi:10.1093/ibd/izy148

High Throughput Screen Identifies Interferon γ-Dependent Inhibitors of Toxoplasma gondii Growth.

Radke JB, Carey KL, Shaw S, et al. High Throughput Screen Identifies Interferon γ-Dependent Inhibitors of Toxoplasma gondii Growth. ACS Infect Dis. 2018;4(10):1499-1507. doi:10.1021/acsinfecdis.8b00135

CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.

Lehrman EK, Wilton DK, Litvina EY, et al. CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron. 2018;100(1):120-134.e6. doi:10.1016/j.neuron.2018.09.017

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.

Schirmer M, Denson L, Vlamakis H, et al. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell Host Microbe. 2018;24(4):600-610.e4. doi:10.1016/j.chom.2018.09.009

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Publications

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