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Publications

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.

Koblan LW, Doman JL, Wilson C, et al. Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nat Biotechnol. 2018;36(9):843-846. doi:10.1038/nbt.4172

The Ancestral Pace of Variant Reclassification.

Plon SE, Rehm HL. The Ancestral Pace of Variant Reclassification. J Natl Cancer Inst. 2018;110(10):1133-1134. doi:10.1093/jnci/djy075

Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum.

Liu L, Tabung FK, Zhang X, et al. Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum. Clin Gastroenterol Hepatol. 2018;16(10):1622-1631.e3. doi:10.1016/j.cgh.2018.04.030

RWEN: response-weighted elastic net for prediction of chemosensitivity of cancer cell lines.

Basu A, Mitra R, Liu H, Schreiber SL, Clemons PA. RWEN: response-weighted elastic net for prediction of chemosensitivity of cancer cell lines. Bioinformatics. 2018;34(19):3332-3339. doi:10.1093/bioinformatics/bty199

All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition.

Fan LZ, Nehme R, Adam Y, et al. All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition. Nat Methods. 2018;15(10):823-831. doi:10.1038/s41592-018-0142-8

Effectiveness of a Web-Based Personalized Rheumatoid Arthritis Risk Tool With or Without a Health Educator for Knowledge of Rheumatoid Arthritis Risk Factors.

Prado MG, Iversen MD, Yu Z, et al. Effectiveness of a Web-Based Personalized Rheumatoid Arthritis Risk Tool With or Without a Health Educator for Knowledge of Rheumatoid Arthritis Risk Factors. Arthritis Care Res (Hoboken). 2018;70(10):1421-1430. doi:10.1002/acr.23510

Metabolic Vulnerabilities of Prostate Cancer: Diagnostic and Therapeutic Opportunities.

Zadra G, Loda M. Metabolic Vulnerabilities of Prostate Cancer: Diagnostic and Therapeutic Opportunities. Cold Spring Harb Perspect Med. 2018;8(10). doi:10.1101/cshperspect.a030569

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.

Reshef YA, Finucane HK, Kelley DR, et al. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. Nat Genet. 2018;50(10):1483-1493. doi:10.1038/s41588-018-0196-7

Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.

Risher C, Kim N, Koh S, et al. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. J Cell Biol. 2018;217(10):3747-3765. doi:10.1083/jcb.201802057

Gene therapy for neurological disorders: progress and prospects.

Deverman BE, Ravina BM, Bankiewicz KS, Paul SM, W Y Sah D. Gene therapy for neurological disorders: progress and prospects. Nat Rev Drug Discov. 2018;17(10):767. doi:10.1038/nrd.2018.158