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Publications

High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast.

Guo X, Chavez A, Tung A, et al. High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast. Nat Biotechnol. 2018;36(6):540-546. doi:10.1038/nbt.4147

Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast.

Young EM, Zhao Z, Gielesen BEM, et al. Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast. Metab Eng. 2018;48:33-43. doi:10.1016/j.ymben.2018.05.002

Transmission of molecularly undetectable circulating parasite clones leads to high infection complexity in mosquitoes post feeding.

Grignard L, Gonçalves BP, Early AM, et al. Transmission of molecularly undetectable circulating parasite clones leads to high infection complexity in mosquitoes post feeding. Int J Parasitol. 2018;48(8):671-677. doi:10.1016/j.ijpara.2018.02.005

De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria.

Redmond SN, MacInnis BM, Bopp S, et al. De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria. Mol Biol Evol. 2018;35(7):1678-1689. doi:10.1093/molbev/msy059

Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, et al. Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. 2018;559(7714):E8. doi:10.1038/s41586-018-0070-x

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

van Zuydam NR, Ahlqvist E, Sandholm N, et al. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. Diabetes. 2018;67(7):1414-1427. doi:10.2337/db17-0914

Searching for superstool: maximizing the therapeutic potential of FMT.

Olesen SW, Leier MM, Alm EJ, Kahn SA. Searching for superstool: maximizing the therapeutic potential of FMT. Nat Rev Gastroenterol Hepatol. 2018;15(7):387-388. doi:10.1038/s41575-018-0019-4

Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities.

Pizzo E, Pane K, Bosso A, et al. Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities. Biochim Biophys Acta Biomembr. 2018;1860(7):1425-1435. doi:10.1016/j.bbamem.2018.04.010

Plasma branched chain/aromatic amino acids, enriched Mediterranean diet and risk of type 2 diabetes: case-cohort study within the PREDIMED Trial.

Ruiz-Canela M, Guasch-Ferré M, Toledo E, et al. Plasma branched chain/aromatic amino acids, enriched Mediterranean diet and risk of type 2 diabetes: case-cohort study within the PREDIMED Trial. Diabetologia. 2018;61(7):1560-1571. doi:10.1007/s00125-018-4611-5

Association Between Obesity and Weight Change and Risk of Diverticulitis in Women.

Ma W, Jovani M, Liu PH, et al. Association Between Obesity and Weight Change and Risk of Diverticulitis in Women. Gastroenterology. 2018;155(1):58-66.e4. doi:10.1053/j.gastro.2018.03.057