ӳ��ý

Publications

De novo NAD biosynthetic impairment in acute kidney injury in humans.

Mehr AP, Tran MT, Ralto KM, et al. De novo NAD biosynthetic impairment in acute kidney injury in humans. Nat Med. 2018;24(9):1351-1359. doi:10.1038/s41591-018-0138-z

Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.

Di Stefano B, Ueda M, Sabri S, et al. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nat Methods. 2018;15(9):732-740. doi:10.1038/s41592-018-0104-1

Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk.

Castel SE, Cervera A, Mohammadi P, et al. Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk. Nat Genet. 2018;50(9):1327-1334. doi:10.1038/s41588-018-0192-y

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.

Durbin AD, Zimmerman MW, Dharia NV, et al. Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nat Genet. 2018;50(9):1240-1246. doi:10.1038/s41588-018-0191-z

Approximate, simultaneous comparison of microbial genome architectures via syntenic anchoring of quiver representations.

Salazar AN, Abeel T. Approximate, simultaneous comparison of microbial genome architectures via syntenic anchoring of quiver representations. Bioinformatics. 2018;34(17):i732-i742. doi:10.1093/bioinformatics/bty614

Dysbiosis of the gut microbiota and colorectal cancer: the key target of molecular pathological epidemiology.

Kosumi K, Mima K, Baba H, Ogino S. Dysbiosis of the gut microbiota and colorectal cancer: the key target of molecular pathological epidemiology. J Lab Precis Med. 2018;3. doi:10.21037/jlpm.2018.09.05

Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma.

Hamieh L, Choueiri TK, Ogórek B, et al. Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma. PLoS Genet. 2018;14(9):e1007679. doi:10.1371/journal.pgen.1007679

Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project.

Christensen KD, Phillips KA, Green RC, Dukhovny D. Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project. Value Health. 2018;21(9):1054-1061. doi:10.1016/j.jval.2018.06.013

Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.

Bellmunt J, Lalani AKA, Jacobus S, et al. Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma. Br J Cancer. 2018;119(6):707-712. doi:10.1038/s41416-018-0261-0

Sex-Specific Association between Family History of Diabetes and Risk of Colorectal Cancer: Two Prospective Cohort Studies.

Ma W, Song M, Kværner AS, et al. Sex-Specific Association between Family History of Diabetes and Risk of Colorectal Cancer: Two Prospective Cohort Studies. Cancer Prev Res (Phila). 2018;11(9):535-544. doi:10.1158/1940-6207.CAPR-18-0159