Diploid donor-specific assembly enhances somatic structural variant detection in cancer genomes. Zhang Y, Qu H, Qin Q, Li H, Park PJ. Diploid donor-specific assembly enhances somatic structural variant detection in cancer genomes. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.28.685155 PMCID PMC12636593 Read more
Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor. Sit B, Sanderlin AG, Zhu CY, Bird LE, Doench JG, Lamason RL. Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.28.684717 PMCID PMC12636401 Read more
An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference. Alemu R, Terskaya A, Howell M, et al. An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference. Research square. 2025. doi:10.21203/rs.3.rs-7828579/v1 PMCID PMC12633171 Read more
Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders. Tamura S, Nelson AD, Spratt PWE, et al. Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders. Nature. 2025. doi:10.1038/s41586-025-09995-9 Read more
Extracellular vesicle delivery of myristoylated Cas9 highlights chromatin accessibility as an efficacy barrier in prostate cancer. Wang S. Extracellular vesicle delivery of myristoylated Cas9 highlights chromatin accessibility as an efficacy barrier in prostate cancer. Molecular therapy : the journal of the American Society of Gene Therapy. 2025. doi:10.1016/j.ymthe.2025.11.037 Read more
Biomaterial-minimalistic photoactivated bioprinting of cell-dense tissues. Wang M, Li W, Hao J, et al. Biomaterial-minimalistic photoactivated bioprinting of cell-dense tissues. Cell. 2025. doi:10.1016/j.cell.2025.11.012 Read more
Targeted protein O-GlcNAc reveals transcriptional functions for O-GlcNAc. Mody AC, Ramirez DH, Woo CM. Targeted protein O-GlcNAc reveals transcriptional functions for O-GlcNAc. Cell chemical biology. 2025. doi:10.1016/j.chembiol.2025.11.003 Read more
Multiplexed detection of febrile infections using CARMEN. Kamariza M, McMahon K, Kim L, et al. Multiplexed detection of febrile infections using CARMEN. Nature communications. 2025. doi:10.1038/s41467-025-66243-4 Read more
Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study. Wang N, Zhang Y, Schroeder P, et al. Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study. Diabetes & metabolism journal. 2025. doi:10.4093/dmj.2025.0557 Read more
Orthogonal Cleavage of the HMPB Linker from Solid Support Using HFIP. Desgagné M, Kutateladze DA, Pentelute BL. Orthogonal Cleavage of the HMPB Linker from Solid Support Using HFIP. Organic letters. 2025. doi:10.1021/acs.orglett.5c04086 Read more