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Publications

IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk.

Zhang L, Omarov M, Xu L, deGoma E, Natarajan P, Georgakis MK. IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk. Nature cardiovascular research. 2025;4(9):1172-1186. doi:10.1038/s44161-025-00700-7

Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.

Lee HG, Rone JM, Li Z, et al. Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature. 2025;645(8081):E5. doi:10.1038/s41586-025-09546-2

Author Correction: Complex genetic variation in nearly complete human genomes.

Logsdon GA, Ebert P, Audano PA, et al. Author Correction: Complex genetic variation in nearly complete human genomes. Nature. 2025;645(8081):E6. doi:10.1038/s41586-025-09547-1

Faithful inheritance: Parental histone recycling and epigenetic memory in fission yeast.

Fang Y, Toda T, Jia S. Faithful inheritance: Parental histone recycling and epigenetic memory in fission yeast. Cell insight. 2025;4(5):100275. doi:10.1016/j.cellin.2025.100275

A Polygenic Risk Score to Predict Incident Heart Failure Across the Spectrum of Cardiovascular Risk.

Haller PM, Melloni GEM, Berg DD, et al. A Polygenic Risk Score to Predict Incident Heart Failure Across the Spectrum of Cardiovascular Risk. Journal of the American College of Cardiology. 2025;86(12):860-873. doi:10.1016/j.jacc.2025.06.050

Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women.

Ezzat D, Uddin MM, Xue L, et al. Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women. Journal of the American College of Cardiology. 2025. doi:10.1016/j.jacc.2025.07.058

Rapid Generation of Hypervariable Chemical Libraries.

Albin JS, Lee GY, Johnson C, Vithanage DA, Vuong W, Pentelute BL. Rapid Generation of Hypervariable Chemical Libraries. Chem. 2025. doi:10.1016/j.chempr.2025.102501

Defining the cell and molecular origins of the primate ovarian reserve.

Wamaitha SE, Rojas EJ, Monticolo F, et al. Defining the cell and molecular origins of the primate ovarian reserve. Nature communications. 2025;16(1):7539. doi:10.1038/s41467-025-62702-0

Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer.

Hong D, Lyu Y, Nayak R, et al. Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer. Developmental cell. 2025. doi:10.1016/j.devcel.2025.07.023

Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores.

Detrois KE, Hartonen T, Teder-Laving M, et al. Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores. Nature genetics. 2025;57(9):2136-2145. doi:10.1038/s41588-025-02298-9