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Publications

Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene.

Mahlman M, Karjalainen MK, Huusko JM, et al. Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene. Sci Rep. 2017;7(1):9271. doi:10.1038/s41598-017-08977-w

Reprogramming Enhancers to Drive Metastasis.

Mostoslavsky R, Bardeesy N. Reprogramming Enhancers to Drive Metastasis. Cell. 2017;170(5):823-825. doi:10.1016/j.cell.2017.08.010

CDK4/6 inhibition triggers anti-tumour immunity.

Goel S, DeCristo MJ, Watt AC, et al. CDK4/6 inhibition triggers anti-tumour immunity. Nature. 2017;548(7668):471-475. doi:10.1038/nature23465

Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.

Kim JW, Abudayyeh OO, Yeerna H, et al. Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States. Cell Syst. 2017;5(2):105-118.e9. doi:10.1016/j.cels.2017.08.002

The GenePattern Notebook Environment.

Reich M, Tabor T, Liefeld T, et al. The GenePattern Notebook Environment. Cell Syst. 2017;5(2):149-151.e1. doi:10.1016/j.cels.2017.07.003

Neuregulin signaling pathway in smoking behavior.

Gupta R, Qaiser B, He L, et al. Neuregulin signaling pathway in smoking behavior. Transl Psychiatry. 2017;7(8):e1212. doi:10.1038/tp.2017.183

Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists.

Boltaev U, Meyer Y, Tolibzoda F, et al. Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists. Sci Signal. 2017;10(493). doi:10.1126/scisignal.aal1670

Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis.

Yousri NA, Bayoumy K, Elhaq WG, et al. Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis. Sci Rep. 2017;7(1):9137. doi:10.1038/s41598-017-05439-1

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells.

Iaconelli J, Lalonde J, Watmuff B, et al. Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS Chem Biol. 2017;12(8):2139-2148. doi:10.1021/acschembio.6b01014

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.

Joung J, Engreitz JM, Konermann S, et al. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. 2017;548(7667):343-346. doi:10.1038/nature23451