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Publications

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis.

May-Wilson S, Sud A, Law PJ, et al. Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis. Eur J Cancer. 2017;84:228-238. doi:10.1016/j.ejca.2017.07.034

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data.

Schep AN, Wu B, Buenrostro JD, Greenleaf WJ. chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data. Nat Methods. 2017;14(10):975-978. doi:10.1038/nmeth.4401

Plasma lipidomic profiles and cardiovascular events in a randomized intervention trial with the Mediterranean diet.

Toledo E, Wang DD, Ruiz-Canela M, et al. Plasma lipidomic profiles and cardiovascular events in a randomized intervention trial with the Mediterranean diet. Am J Clin Nutr. 2017;106(4):973-983. doi:10.3945/ajcn.116.151159

A genetically encoded tool for manipulation of NADP/NADPH in living cells.

Cracan V, Titov DV, Shen H, Grabarek Z, Mootha VK. A genetically encoded tool for manipulation of NADP/NADPH in living cells. Nat Chem Biol. 2017;13(10):1088-1095. doi:10.1038/nchembio.2454

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.

Chow RD, Guzman CD, Wang G, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nat Neurosci. 2017;20(10):1329-1341. doi:10.1038/nn.4620

Deep sequencing of RSV from an adult challenge study and from naturally infected infants reveals heterogeneous diversification dynamics.

Lau JW, Kim YI, Murphy R, et al. Deep sequencing of RSV from an adult challenge study and from naturally infected infants reveals heterogeneous diversification dynamics. Virology. 2017;510:289-296. doi:10.1016/j.virol.2017.07.017

Pathways from assaultive violence to post-traumatic stress, depression, and generalized anxiety symptoms through stressful life events: longitudinal mediation models.

Lowe SR, Joshi S, Galea S, et al. Pathways from assaultive violence to post-traumatic stress, depression, and generalized anxiety symptoms through stressful life events: longitudinal mediation models. Psychol Med. 2017;47(14):2556-2566. doi:10.1017/S0033291717001143

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

Legge SE, Hamshere ML, Ripke S, et al. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Mol Psychiatry. 2017;22(10):1509. doi:10.1038/mp.2016.137

Posttraumatic stress disorder in the World Mental Health Surveys.

Koenen KC, Ratanatharathorn A, Ng L, et al. Posttraumatic stress disorder in the World Mental Health Surveys. Psychol Med. 2017;47(13):2260-2274. doi:10.1017/S0033291717000708

Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

Gazal S, Finucane HK, Furlotte NA, et al. Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. Nat Genet. 2017;49(10):1421-1427. doi:10.1038/ng.3954