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Publications

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.

Nomura A, Won HH, Khera AV, et al. Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease. Circ Res. 2017;121(1):81-88. doi:10.1161/CIRCRESAHA.117.311145

Chemical transformation of xenobiotics by the human gut microbiota.

Koppel N, Rekdal VM, Balskus EP. Chemical transformation of xenobiotics by the human gut microbiota. Science. 2017;356(6344). doi:10.1126/science.aag2770

Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.

Xue Y, Mezzavilla M, Haber M, et al. Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. Nat Commun. 2017;8:15927. doi:10.1038/ncomms15927

Deinococcus Mn-peptide complex: A novel approach to alphavirus vaccine development.

Gayen M, Gupta P, Morazzani EM, et al. Deinococcus Mn-peptide complex: A novel approach to alphavirus vaccine development. Vaccine. 2017;35(29):3672-3681. doi:10.1016/j.vaccine.2017.05.016

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.

Spaulding CN, Klein RD, Ruer S, et al. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature. 2017;546(7659):528-532. doi:10.1038/nature22972

Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases.

Palomo V, Perez DI, Roca C, et al. Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases. J Med Chem. 2017;60(12):4983-5001. doi:10.1021/acs.jmedchem.7b00395

Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.

Huang AY, Yu D, Davis LK, et al. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 2017;94(6):1101-1111.e7. doi:10.1016/j.neuron.2017.06.010

Defining the 5΄ and 3΄ landscape of the Drosophila transcriptome with Exo-seq and RNaseH-seq.

Afik S, Bartok O, Artyomov MN, et al. Defining the 5΄ and 3΄ landscape of the Drosophila transcriptome with Exo-seq and RNaseH-seq. Nucleic Acids Res. 2017;45(11):e95. doi:10.1093/nar/gkx133

An Experimental Framework for Quantifying Bacterial Tolerance.

Brauner A, Shoresh N, Fridman O, Balaban NQ. An Experimental Framework for Quantifying Bacterial Tolerance. Biophys J. 2017;112(12):2664-2671. doi:10.1016/j.bpj.2017.05.014

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt SH, Streit F, Jungkunz M, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry. 2017;7(6):e1155. doi:10.1038/tp.2017.115