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Publications

The complex genetics of gait speed: genome-wide meta-analysis approach.

Ben-Avraham D, Karasik D, Verghese J, et al. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017;9(1):209-246. doi:10.18632/aging.101151

A working model of the deep relationships of diverse modern human genetic lineages outside of Africa.

Lipson M, Reich D. A working model of the deep relationships of diverse modern human genetic lineages outside of Africa. Mol Biol Evol. 2017. doi:10.1093/molbev/msw293

The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.

Chang H, Hoshina N, Zhang C, et al. The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Mol Psychiatry. 2017. doi:10.1038/mp.2016.231

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO. Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017;7:40495. doi:10.1038/srep40495

Starved epithelial cells uptake extracellular matrix for survival.

Muranen T, Iwanicki MP, Curry NL, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989. doi:10.1038/ncomms13989

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.

Charney AW, Ruderfer DM, Stahl EA, et al. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl Psychiatry. 2017;7(1):e993. doi:10.1038/tp.2016.242

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

Tsvetkov P, Sokol E, Jin D, et al. Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers. Proc Natl Acad Sci U S A. 2017;114(2):382-387. doi:10.1073/pnas.1619067114

Restriction to gene flow is associated with changes in the molecular basis of pyrethroid resistance in the malaria vector Anopheles funestus.

Barnes KG, Irving H, Chiumia M, et al. Restriction to gene flow is associated with changes in the molecular basis of pyrethroid resistance in the malaria vector Anopheles funestus. Proc Natl Acad Sci U S A. 2017;114(2):286-291. doi:10.1073/pnas.1615458114

Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond.

Vasta JD, Choudhary A, Jensen KH, McGrath NA, Raines RT. Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond. Biochemistry. 2017;56(1):219-227. doi:10.1021/acs.biochem.6b00976

A multi-step classifier addressing cohort heterogeneity improves performance of prognostic biomarkers in three cancer types.

Patrick E, Schramm SJ, Ormerod JT, et al. A multi-step classifier addressing cohort heterogeneity improves performance of prognostic biomarkers in three cancer types. Oncotarget. 2017;8(2):2807-2815. doi:10.18632/oncotarget.13203