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Publications

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

Oosting M, Kerstholt M, Horst RT, et al. Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans. Cell Host Microbe. 2016;20(6):822-833. doi:10.1016/j.chom.2016.10.006

Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China.

Bi Y, Chen Q, Wang Q, et al. Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China. Cell Host Microbe. 2016;20(6):810-821. doi:10.1016/j.chom.2016.10.022

Genetic Obesity and the Risk of Atrial Fibrillation- Causal Estimates from Mendelian Randomization.

Chatterjee NA, Giulianini F, Geelhoed B, et al. Genetic Obesity and the Risk of Atrial Fibrillation- Causal Estimates from Mendelian Randomization. Circulation. 2016. doi:10.1161/CIRCULATIONAHA.116.024921

A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation.

Lessing D, Dial TO, Wei C, et al. A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation. Proc Natl Acad Sci U S A. 2016;113(50):14366-14371. doi:10.1073/pnas.1617597113

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.

Arts RJW, Novakovic B, Horst RT, et al. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016;24(6):807-819. doi:10.1016/j.cmet.2016.10.008

A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development.

Hill JH, Franzosa EA, Huttenhower C, Guillemin K. A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development. Elife. 2016;5. doi:10.7554/eLife.20145

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation.

Graham DB, Lefkovith A, Deelen P, et al. TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation. Cell Rep. 2016;17(11):2955-2965. doi:10.1016/j.celrep.2016.11.042

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.

Arroyo JD, Jourdain AA, Calvo SE, et al. A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation. Cell Metab. 2016;24(6):875-885. doi:10.1016/j.cmet.2016.08.017

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer.

Henry WS, Hendrickson DG, Beca F, et al. LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer. Oncotarget. 2016;7(50):81981-81994. doi:10.18632/oncotarget.11962

Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.

Nakagawa S, Wei L, Song WM, et al. Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition. Cancer Cell. 2016;30(6):879-890. doi:10.1016/j.ccell.2016.11.004