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Publications

Enzyme-Activated Sugar-Coated Bifunctional Degraders.

Zhu Q, Fischer G, Cheng SS, et al. Enzyme-Activated Sugar-Coated Bifunctional Degraders. Journal of the American Chemical Society. 2025;147(38):34672-34680. doi:10.1021/jacs.5c09843

Maternal-infant rotavirus-specific antibody kinetics to inform timing of vaccine boosting in Malawi: An observational study.

Mandolo J, Mulira L, Moyo M, et al. Maternal-infant rotavirus-specific antibody kinetics to inform timing of vaccine boosting in Malawi: An observational study. PLoS medicine. 2025;22(9):e1004734. doi:10.1371/journal.pmed.1004734

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Chami N, Wang Z, Svenstrup V, et al. Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities. Nature medicine. 2025. doi:10.1038/s41591-025-03931-0

Applying weighted Cox regression to genome-wide association studies of time-to-event phenotypes.

Li Y, Ma Y, Xu H, et al. Applying weighted Cox regression to genome-wide association studies of time-to-event phenotypes. Nature computational science. 2025. doi:10.1038/s43588-025-00864-z

CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate.

Okechukwu CC, Ma X, Li W, et al. CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate. Cancers. 2025;17(17). doi:10.3390/cancers17172739

Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers.

Westerman KE, Chasman DI, Gauderman J, Durvasula A. Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers. HGG advances. 2025;7(1):100515. doi:10.1016/j.xhgg.2025.100515

Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation.

Liao G, Nakayama T, Zhu B, et al. Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation. Immunity. 2025. doi:10.1016/j.immuni.2025.08.009

Towards modeling evolving longitudinal health trajectories with a transformer-based deep learning model.

Moen H, Raj V, Vabalas A, et al. Towards modeling evolving longitudinal health trajectories with a transformer-based deep learning model. Annals of epidemiology. 2025;111:30-43. doi:10.1016/j.annepidem.2025.08.025

Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice.

Murach KA, Dungan CM, Chambers TL, et al. Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice. Aging cell. 2025:e70236. doi:10.1111/acel.70236

An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans.

Safina KR, Kotliar DA, Curtis M, et al. An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.01.673389