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Publications

Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays.

Ippoliti PJ, Kuhn E, Mani DR, et al. Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays. Anal Chem. 2016;88(15):7548-55. doi:10.1021/acs.analchem.6b00946

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.

Farfel JM, Yu L, Buchman AS, Schneider JA, De Jager PL, Bennett DA. Relation of genomic variants for Alzheimer disease dementia to common neuropathologies. Neurology. 2016;87(5):489-96. doi:10.1212/WNL.0000000000002909

Polygenic risk of Alzheimer disease is associated with early- and late-life processes.

Mormino EC, Sperling RA, Holmes AJ, et al. Polygenic risk of Alzheimer disease is associated with early- and late-life processes. Neurology. 2016;87(5):481-8. doi:10.1212/WNL.0000000000002922

Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.

Darrow EM, Huntley MH, Dudchenko O, et al. Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture. Proc Natl Acad Sci U S A. 2016;113(31):E4504-12. doi:10.1073/pnas.1609643113

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.

Brundin L, Sellgren CM, Lim CK, et al. An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. Transl Psychiatry. 2016;6(8):e865. doi:10.1038/tp.2016.133

Genomic determinants of cancer immunotherapy.

Miao D, Van Allen EM. Genomic determinants of cancer immunotherapy. Curr Opin Immunol. 2016;41:32-8. doi:10.1016/j.coi.2016.05.010

Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.

Sajuthi SP, Sharma NK, Chou JW, et al. Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity. Hum Genet. 2016;135(8):869-80. doi:10.1007/s00439-016-1680-8

Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.

Chen G, McQuade JL, Panka DJ, et al. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol. 2016;2(8):1056-64. doi:10.1001/jamaoncol.2016.0509

A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus.

Waters NR, Samuels DJ, Behera RK, et al. A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus. Mol Microbiol. 2016;101(3):495-514. doi:10.1111/mmi.13404

Differential dopaminergic regulation of inwardly rectifying potassium channel mediated subthreshold dynamics in striatal medium spiny neurons.

Zhao B, Zhu J, Dai D, et al. Differential dopaminergic regulation of inwardly rectifying potassium channel mediated subthreshold dynamics in striatal medium spiny neurons. Neuropharmacology. 2016;107:396-410. doi:10.1016/j.neuropharm.2016.03.037