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Publications

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.

Dirice E, Walpita D, Vetere A, et al. Inhibition of DYRK1A Stimulates Human β-Cell Proliferation. Diabetes. 2016;65(6):1660-71. doi:10.2337/db15-1127

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.

Lane JM, Chang AM, Bjonnes AC, et al. Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology. Diabetes. 2016;65(6):1741-51. doi:10.2337/db15-0999

Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells.

Watmuff B, Berkovitch SS, Huang JH, Iaconelli J, Toffel S, Karmacharya R. Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells. Mol Cell Neurosci. 2016;73:96-103. doi:10.1016/j.mcn.2016.01.003

Circulating Metabolites and Survival Among Patients With Pancreatic Cancer.

Yuan C, Clish CB, Wu C, et al. Circulating Metabolites and Survival Among Patients With Pancreatic Cancer. J Natl Cancer Inst. 2016;108(6):djv409. doi:10.1093/jnci/djv409

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Winkler TW, Justice AE, Graff M, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2016;12(6):e1006166. doi:10.1371/journal.pgen.1006166

Genome-wide autozygosity is associated with lower general cognitive ability.

Howrigan DP, Simonson MA, Davies G, et al. Genome-wide autozygosity is associated with lower general cognitive ability. Mol Psychiatry. 2016;21(6):837-43. doi:10.1038/mp.2015.120

Phenotypic extremes in rare variant study designs.

Peloso GM, Rader DJ, Gabriel S, Kathiresan S, Daly MJ, Neale BM. Phenotypic extremes in rare variant study designs. Eur J Hum Genet. 2016;24(6):924-30. doi:10.1038/ejhg.2015.197

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.

Orlando G, Law PJ, Palin K, et al. Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. Hum Mol Genet. 2016;25(11):2349-2359. doi:10.1093/hmg/ddw087

An open-source computational tool to automatically quantify immunolabeled retinal ganglion cells.

Dordea AC, Bray MA, Allen K, et al. An open-source computational tool to automatically quantify immunolabeled retinal ganglion cells. Exp Eye Res. 2016;147:50-6. doi:10.1016/j.exer.2016.04.012

Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.

Joyal JS, Sun Y, Gantner ML, et al. Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nature medicine. 2016;22(6):692. doi:10.1038/nm0616-692a