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Publications

An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites.

Ferreira MSV, Bergmann C, Bodensiek I, et al. An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites. J Hematol Oncol. 2016;9:4. doi:10.1186/s13045-016-0234-9

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Nelson CE, Hakim CH, Ousterout DG, et al. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science. 2016;351(6271):403-7. doi:10.1126/science.aad5143

In vivo gene editing in dystrophic mouse muscle and muscle stem cells.

Tabebordbar M, Zhu K, Cheng JKW, et al. In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science. 2016;351(6271):407-11. doi:10.1126/science.aad5177

Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.

Cottrell JR, Li B, Kyung JW, et al. Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis. J Biol Chem. 2016;291(4):1948-56. doi:10.1074/jbc.M115.705319

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Pattaro C, Teumer A, Gorski M, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016;7:10023. doi:10.1038/ncomms10023

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.

Shu S, Lin CY, He HH, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529(7586):413-7. doi:10.1038/nature16508

Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases.

Hu JH, Davis KM, Liu DR. Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases. Cell Chem Biol. 2016;23(1):57-73. doi:10.1016/j.chembiol.2015.12.009

The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods.

Wagner BK, Schreiber SL. The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods. Cell Chem Biol. 2016;23(1):3-9. doi:10.1016/j.chembiol.2015.11.008

Information Technology Support for Clinical Genetic Testing within an Academic Medical Center.

Aronson S, Mahanta L, Ros LL, et al. Information Technology Support for Clinical Genetic Testing within an Academic Medical Center. J Pers Med. 2016;6(1). doi:10.3390/jpm6010004

An eMERGE Clinical Center at Partners Personalized Medicine.

Smoller JW, Karlson EW, Green RC, et al. An eMERGE Clinical Center at Partners Personalized Medicine. J Pers Med. 2016;6(1). doi:10.3390/jpm6010005