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Publications

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.

Chantranupong L, Scaria SM, Saxton RA, et al. The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. Cell. 2016;165(1):153-64. doi:10.1016/j.cell.2016.02.035

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Stitziel NO, Stirrups KE, et al. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med. 2016;374(12):1134-44. doi:10.1056/NEJMoa1507652

System-wide Analysis of the T Cell Response.

Covacu R, Philip H, Jaronen M, et al. System-wide Analysis of the T Cell Response. Cell Rep. 2016;14(11):2733-44. doi:10.1016/j.celrep.2016.02.056

Reducing Cardiovascular Risk Using Genomic Information in the Era of Precision Medicine.

Natarajan P, O’Donnell CJ. Reducing Cardiovascular Risk Using Genomic Information in the Era of Precision Medicine. Circulation. 2016;133(12):1155-9. doi:10.1161/CIRCULATIONAHA.116.021765

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.

Kim N, Cho A, Watanabe H, et al. Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation. Oncotarget. 2016;7(12):13797-809. doi:10.18632/oncotarget.7318

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.

Strickland KC, Howitt BE, Shukla SA, et al. Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer. Oncotarget. 2016;7(12):13587-98. doi:10.18632/oncotarget.7277

Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures.

Lu Y, Zhong C, Wang L, et al. Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nat Commun. 2016;7:10962. doi:10.1038/ncomms10962

Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients.

Ruan Y, Jiang J, Guo L, et al. Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients. Sci Rep. 2016;6:23368. doi:10.1038/srep23368

Molecular sled sequences are common in mammalian proteins.

Xiong K, Blainey PC. Molecular sled sequences are common in mammalian proteins. Nucleic Acids Res. 2016;44(5):2266-73. doi:10.1093/nar/gkw035

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.

Howitt MR, Lavoie S, Michaud M, et al. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science. 2016;351(6279):1329-33. doi:10.1126/science.aaf1648