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Publications

Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo.

Li M, Tao Y, Shu Y, et al. Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo. J Am Chem Soc. 2015;137(44):14084-93. doi:10.1021/jacs.5b05694

Shared genetic aetiology of puberty timing between sexes and with health-related outcomes.

Day FR, Bulik-Sullivan B, Hinds DA, et al. Shared genetic aetiology of puberty timing between sexes and with health-related outcomes. Nat Commun. 2015;6:8842. doi:10.1038/ncomms9842

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.

Shmakov S, Abudayyeh OO, Makarova KS, et al. Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems. Mol Cell. 2015;60(3):385-97. doi:10.1016/j.molcel.2015.10.008

Draft Genome Sequence of Cercospora arachidicola, Causal Agent of Early Leaf Spot in Peanuts.

Orner VA, Cantonwine EG, Wang XM, et al. Draft Genome Sequence of Cercospora arachidicola, Causal Agent of Early Leaf Spot in Peanuts. Genome Announc. 2015;3(6). doi:10.1128/genomeA.01281-15

Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.

Tucker G, Loh PR, MacLeod IM, et al. Two-Variance-Component Model Improves Genetic Prediction in Family Datasets. Am J Hum Genet. 2015;97(5):677-90. doi:10.1016/j.ajhg.2015.10.002

Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy.

Ng SY, Soh BS, Rodriguez-Muela N, et al. Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy. Cell Stem Cell. 2015;17(5):569-84. doi:10.1016/j.stem.2015.08.003

Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.

Strohecker AM, Joshi S, Possemato R, Abraham RT, Sabatini DM, White E. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015;34(45):5662-76. doi:10.1038/onc.2015.23

CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.

Bray MA, Carpenter AE. CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data. BMC Bioinformatics. 2015;16:368. doi:10.1186/s12859-015-0759-x

Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.

Karaca E, Harel T, Pehlivan D, et al. Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease. Neuron. 2015;88(3):499-513. doi:10.1016/j.neuron.2015.09.048

Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons.

Ye Z, Mostajo-Radji MA, Brown JR, et al. Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons. Neuron. 2015;88(3):475-83. doi:10.1016/j.neuron.2015.10.006