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Publications

Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex.

Jenkins AM, Waterhouse RM, Muskavitch MAT. Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex. BMC Genomics. 2015;16:337. doi:10.1186/s12864-015-1507-3

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

Yin X, Low HQ, Wang L, et al. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun. 2015;6:6916. doi:10.1038/ncomms7916

Widespread macromolecular interaction perturbations in human genetic disorders.

Sahni N, Yi S, Taipale M, et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 2015;161(3):647-60. doi:10.1016/j.cell.2015.04.013

Toward the rational design of carbapenem uptake in Pseudomonas aeruginosa.

Isabella VM, Campbell AJ, Manchester J, et al. Toward the rational design of carbapenem uptake in Pseudomonas aeruginosa. Chem Biol. 2015;22(4):535-47. doi:10.1016/j.chembiol.2015.03.018

Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism.

Olson DE, Sleiman SF, Bourassa MW, et al. Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism. Chem Biol. 2015;22(4):439-445. doi:10.1016/j.chembiol.2015.03.014

Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells.

Wang J, Mikse O, Liao RG, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34(17):2167-77. doi:10.1038/onc.2014.161

Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP.

Kathiresan S. Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP. J Am Coll Cardiol. 2015;65(15):1562-6. doi:10.1016/j.jacc.2015.02.049

Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

Schafer DP, Stevens B. Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages. Immunity. 2015;42(4):600-2. doi:10.1016/j.immuni.2015.04.002

Pugh et al. reply.

Pugh TJ, Banerji S, Meyerson M. Pugh et al. reply. Nature. 2015;520(7547):E12-4. doi:10.1038/nature14266

Calibrating genomic and allelic coverage bias in single-cell sequencing.

Zhang CZ, Adalsteinsson VA, Francis J, et al. Calibrating genomic and allelic coverage bias in single-cell sequencing. Nat Commun. 2015;6:6822. doi:10.1038/ncomms7822