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Publications

Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models.

Karr JR, Williams AH, Zucker JD, et al. Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models. PLoS Comput Biol. 2015;11(5):e1004096. doi:10.1371/journal.pcbi.1004096

Entropic Description of Gas Hydrate Ice-Liquid Equilibrium via Enhanced Sampling of Coexisting Phases.

Małolepsza E, Kim J, Keyes T. Entropic Description of Gas Hydrate Ice-Liquid Equilibrium via Enhanced Sampling of Coexisting Phases. Physical review letters. 2015;114(17):170601. http://link.aps.org/abstract/PRL/v114/p170601

CRISPR germline engineering--the community speaks.

Bosley KS, Botchan M, Bredenoord AL, et al. CRISPR germline engineering--the community speaks. Nat Biotechnol. 2015;33(5):478-86. doi:10.1038/nbt.3227

Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast.

Csárdi G, Franks A, Choi DS, Airoldi EM, Drummond A. Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast. PLoS Genet. 2015;11(5):e1005206. doi:10.1371/journal.pgen.1005206

Cell Specific eQTL Analysis without Sorting Cells.

Westra HJ, Arends D, Esko T, et al. Cell Specific eQTL Analysis without Sorting Cells. PLoS Genet. 2015;11(5):e1005223. doi:10.1371/journal.pgen.1005223

Noncoding RNAs connect genetic risk factors to the neurodevelopmental basis of bipolar disorder.

Bavamian S, Mellios N, Lalonde J, et al. Noncoding RNAs connect genetic risk factors to the neurodevelopmental basis of bipolar disorder. Mol Psychiatry. 2015;20(5):548. doi:10.1038/mp.2015.51

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

Etchegaray JP, Chavez L, Huang Y, et al. The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nat Cell Biol. 2015;17(5):545-57. doi:10.1038/ncb3147

Spatial reconstruction of single-cell gene expression data.

Satija R, Farrell JA, Gennert D, Schier AF, Regev A. Spatial reconstruction of single-cell gene expression data. Nat Biotechnol. 2015;33(5):495-502. doi:10.1038/nbt.3192

High-throughput functional genomics using CRISPR-Cas9.

Shalem O, Sanjana NE, Zhang F. High-throughput functional genomics using CRISPR-Cas9. Nat Rev Genet. 2015;16(5):299-311. doi:10.1038/nrg3899

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction.

Akizu N, Cantagrel V, Zaki MS, et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;47(5):528-34. doi:10.1038/ng.3256