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Publications

Chromatin regulation at the frontier of synthetic biology.

Keung AJ, Joung K, Khalil AS, Collins JJ. Chromatin regulation at the frontier of synthetic biology. Nat Rev Genet. 2015;16(3):159-71. doi:10.1038/nrg3900

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.

Kim H, Zheng S, Amini SS, et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Res. 2015;25(3):316-27. doi:10.1101/gr.180612.114

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

French A, Bravery C, Smith J, et al. Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards. Stem Cells Transl Med. 2015;4(3):217-23. doi:10.5966/sctm.2014-0233

Therapeutic insights from genomic studies of head and neck squamous cell carcinomas.

Hammerman PS, Hayes N, Grandis JR. Therapeutic insights from genomic studies of head and neck squamous cell carcinomas. Cancer Discov. 2015;5(3):239-44. doi:10.1158/2159-8290.CD-14-1205

Famine versus feast: understanding the metabolism of tumors in vivo.

Mayers JR, Heiden MGV. Famine versus feast: understanding the metabolism of tumors in vivo. Trends Biochem Sci. 2015;40(3):130-40. doi:10.1016/j.tibs.2015.01.004

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.

Bulik-Sullivan BK, Loh PR, Finucane HK, et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015;47(3):291-5. doi:10.1038/ng.3211

Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.

Liu H, Irwanto A, Fu X, et al. Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy. Nat Genet. 2015;47(3):267-71. doi:10.1038/ng.3212

Efficient Bayesian mixed-model analysis increases association power in large cohorts.

Loh PR, Tucker G, Bulik-Sullivan BK, et al. Efficient Bayesian mixed-model analysis increases association power in large cohorts. Nat Genet. 2015;47(3):284-90. doi:10.1038/ng.3190

Large multiallelic copy number variations in humans.

Handsaker RE, Van Doren V, Berman JR, et al. Large multiallelic copy number variations in humans. Nat Genet. 2015;47(3):296-303. doi:10.1038/ng.3200

Convergent evolution of the genomes of marine mammals.

Foote AD, Liu Y, Thomas GWC, et al. Convergent evolution of the genomes of marine mammals. Nat Genet. 2015;47(3):272-5. doi:10.1038/ng.3198