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Publications

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.

Merkle FT, Maroof A, Wataya T, et al. Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development. 2015;142(4):633-43. doi:10.1242/dev.117978

Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus.

Karp PD, Berger B, Kovats D, et al. Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus. Bioinformatics. 2015;31(4):616-7. doi:10.1093/bioinformatics/btv019

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.

Rahmioglu N, Macgregor S, Drong AW, et al. Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum Mol Genet. 2015;24(4):1185-99. doi:10.1093/hmg/ddu516

A novel common variant in DCST2 is associated with length in early life and height in adulthood.

van der Valk RJP, Kreiner-Møller E, Kooijman MN, et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet. 2015;24(4):1155-68. doi:10.1093/hmg/ddu510

Drug discovery. Tying up a transcription factor.

Chen A, Koehler AN. Drug discovery. Tying up a transcription factor. Science. 2015;347(6223):713-4. doi:10.1126/science.aaa6119

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D, Winkler TW, Croteau-Chonka DC, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187-96. doi:10.1038/nature14132

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206. doi:10.1038/nature14177

Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment.

Rudenko A, Seo J, Hu J, et al. Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment. J Neurosci. 2015;35(6):2372-83. doi:10.1523/JNEUROSCI.0969-14.2015

The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes.

Kostic AD, Gevers D, Siljander H, et al. The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. Cell Host Microbe. 2015;17(2):260-73. doi:10.1016/j.chom.2015.01.001

NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma.

Wang H, Pan JQ, Luo L, et al. NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma. Mol Cancer. 2015;14:2. doi:10.1186/1476-4598-14-2