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Publications

The development of the ICD-11 Clinical Descriptions and Diagnostic Guidelines for Mental and Behavioural Disorders.

First MB, Reed GM, Hyman SE, Saxena S. The development of the ICD-11 Clinical Descriptions and Diagnostic Guidelines for Mental and Behavioural Disorders. World Psychiatry. 2015;14(1):82-90. doi:10.1002/wps.20189

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.

Palsson-McDermott EM, Curtis AM, Goel G, et al. Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. Cell metabolism. 2015;21(2):347. doi:10.1016/j.cmet.2015.01.017

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.

Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci. 2015;18(2):199-209. doi:10.1038/nn.3922

Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution.

Cabili MN, Dunagin MC, McClanahan PD, et al. Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. Genome Biol. 2015;16:20. doi:10.1186/s13059-015-0586-4

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Wessel J, Chu AY, Willems SM, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015;6:5897. doi:10.1038/ncomms6897

Disease-specific alterations in the enteric virome in inflammatory bowel disease.

Norman JM, Handley SA, Baldridge MT, et al. Disease-specific alterations in the enteric virome in inflammatory bowel disease. Cell. 2015;160(3):447-60. doi:10.1016/j.cell.2015.01.002

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Konermann S, Brigham MD, Trevino AE, et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 2015;517(7536):583-8. doi:10.1038/nature14136

Targeted antithrombotic protein micelles.

Kim W, Haller C, Dai E, et al. Targeted antithrombotic protein micelles. Angew Chem Int Ed Engl. 2015;54(5):1461-5. doi:10.1002/anie.201408529

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.

Betz RC, Petukhova L, Ripke S, et al. Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. Nat Commun. 2015;6:5966. doi:10.1038/ncomms6966

Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.

Xu J, Shao Z, Li D, et al. Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions. Mol Cell. 2015;57(2):304-16. doi:10.1016/j.molcel.2014.12.009