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Publications

Clinical and Therapeutic Implications of Clonal Hematopoiesis.

Petrone G, Turker I, Natarajan P, Bolton KL. Clinical and Therapeutic Implications of Clonal Hematopoiesis. Annual review of genomics and human genetics. 2024;25(1):329-351. doi:10.1146/annurev-genom-120722-100409

A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia.

Koedijk JB, van der Werf I, Penter L, et al. A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia. Leukemia. 2024. doi:10.1038/s41375-024-02381-w

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Yuan K, Longchamps RJ, Pardiñas AF, et al. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. Nature genetics. 2024. doi:10.1038/s41588-024-01870-z

Integration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis.

Stott KE, Mohabir JT, Bowers K, et al. Integration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis. mBio. 2024:e0159224. doi:10.1128/mbio.01592-24

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Yuan K, Longchamps RJ, Pardiñas AF, et al. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. Nature genetics. 2024. doi:10.1038/s41588-024-01870-z

Diffusion barriers imposed by tissue topology shape Hedgehog morphogen gradients.

Schlissel G, Meziane M, Narducci D, Hansen AS, Li P. Diffusion barriers imposed by tissue topology shape Hedgehog morphogen gradients. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(36):e2400677121. doi:10.1073/pnas.2400677121

Bacterial strain sharing between humans, animals, and the environment among urban households.

Kim DD, Swarthout JM, Worby CJ, et al. Bacterial strain sharing between humans, animals, and the environment among urban households. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.08.05.24311509

A foundation model for clinician-centered drug repurposing.

Huang K, Chandak P, Wang Q, et al. A foundation model for clinician-centered drug repurposing. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2023.03.19.23287458

Scalable imaging-free spatial genomics through computational reconstruction.

Hu C, Borji M, Marrero GJ, et al. Scalable imaging-free spatial genomics through computational reconstruction. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.08.05.606465

Improved high quality sand fly assemblies enabled by ultra low input long read sequencing.

Huang M, Kingan S, Shoue D, et al. Improved high quality sand fly assemblies enabled by ultra low input long read sequencing. Scientific data. 2024;11(1):918. doi:10.1038/s41597-024-03628-y