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Publications

Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes.

Schattgen S, Vegesana K, Hazelton WD, et al. Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.31.657155

Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts.

Konigsberg IR, Vargas LB, Pratte KA, et al. Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.01.25328699

A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.

Atabaki NN, Coral DE, Pomares-Millan H, et al. A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.02.25328773

Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk.

Cudic M, Tubbs JD, Ge T, Smoller JW. Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.04.25328987

Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior.

Gunter-Rahman F, Mallett S, White F, et al. Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior. iScience. 2025;28(6):112636. doi:10.1016/j.isci.2025.112636

Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation.

Kaas M, Chofflet N, Bicer D, et al. Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation. Research square. 2025. doi:10.21203/rs.3.rs-5928514/v1

Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape.

Muir DF, Asper GPR, Notin P, et al. Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape. Science (New York, N.Y.). 2025;388(6752):eadu1058. doi:10.1126/science.adu1058

Pan-viral ORFs discovery using massively parallel ribosome profiling.

Weingarten-Gabbay S, Bauer MR, Stanton AC, et al. Pan-viral ORFs discovery using massively parallel ribosome profiling. Science (New York, N.Y.). 2025;388(6752):1218-1224. doi:10.1126/science.ado6670

Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems.

Bozym DJ, Zheng DX, Revach OY, Aref A, Jenkins RW. Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems. Lab on a chip. 2025;25(13):3038-3059. doi:10.1039/d5lc00062a

Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV-Positive Cancer Cells.

Avenhaus A, Kuhn BJ, Velimirović M, et al. Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV-Positive Cancer Cells. Journal of medical virology. 2025;97(6):e70434. doi:10.1002/jmv.70434