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Publications

Endothelial injury and dysfunction with emerging immunotherapies in multiple myeloma, the impact of COVID-19, and endothelial protection with a focus on the evolving role of defibrotide.

Mo CC, Richardson E, Calabretta E, et al. Endothelial injury and dysfunction with emerging immunotherapies in multiple myeloma, the impact of COVID-19, and endothelial protection with a focus on the evolving role of defibrotide. Blood reviews. 2024:101218. doi:10.1016/j.blre.2024.101218

Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders.

Tomasi J, Lisoway AJ, Zai CC, et al. Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders. Psychiatry research. 2024;338:115982. doi:10.1016/j.psychres.2024.115982

Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders.

Tomasi J, Lisoway AJ, Zai CC, et al. Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders. Psychiatry research. 2024;338:115982. doi:10.1016/j.psychres.2024.115982

Structure-based virtual screening of vast chemical space as a starting point for drug discovery.

Carlsson J, Luttens A. Structure-based virtual screening of vast chemical space as a starting point for drug discovery. Current opinion in structural biology. 2024;87:102829. doi:10.1016/j.sbi.2024.102829

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries.

Misek SA, Fultineer A, Kalfon J, et al. Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications. 2024;15(1):4892. doi:10.1038/s41467-024-48957-z

Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color.

Kim B, Kim DS, Shin JG, et al. Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color. Nature communications. 2024;15(1):4874. doi:10.1038/s41467-024-49031-4

MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease.

Urbut SM, Yeung MW, Khurshid S, et al. MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease. Nature communications. 2024;15(1):4884. doi:10.1038/s41467-024-49296-9

Accelerating Genome- and Phenome-Wide Association Studies using GPUs - A case study using data from the Million Veteran Program.

Rodriguez A, Kim Y, Nandi TN, et al. Accelerating Genome- and Phenome-Wide Association Studies using GPUs - A case study using data from the Million Veteran Program. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.05.17.594583

Scanorama: integrating large and diverse single-cell transcriptomic datasets.

Hie BL, Kim S, Rando TA, Bryson B, Berger B. Scanorama: integrating large and diverse single-cell transcriptomic datasets. Nature protocols. 2024. doi:10.1038/s41596-024-00991-3

Tricyclononenes and tricyclononadienes as efficient monomers for controlled ROMP: understanding structure-propagation rate relationships and enabling facile post-polymerization modification.

Kilgallon LJ, McFadden TP, Sigman MS, Johnson JA. Tricyclononenes and tricyclononadienes as efficient monomers for controlled ROMP: understanding structure-propagation rate relationships and enabling facile post-polymerization modification. Chemical science. 2024;15(22):8334-8345. doi:10.1039/d4sc01986e