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Publications

Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.

Truex NL, Mohapatra S, Melo M, et al. Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. ACS central science. 2024;10(4):793-802. doi:10.1021/acscentsci.3c01544

Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia.

Wang R, Lu JY, Herbert D, et al. Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia. Human psychopharmacology. 2024:e2898. doi:10.1002/hup.2898

Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia.

Wang R, Lu JY, Herbert D, et al. Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia. Human psychopharmacology. 2024:e2898. doi:10.1002/hup.2898

Wastewater based epidemiology as a public health resource in low- and middle-income settings.

Hamilton KA, Wade MJ, Barnes KG, Street RA, Paterson S. Wastewater based epidemiology as a public health resource in low- and middle-income settings. Environmental pollution (Barking, Essex : 1987). 2024:124045. doi:10.1016/j.envpol.2024.124045

Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform.

Anvar NE, Lin C, Ma X, et al. Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform. Nature communications. 2024;15(1):3577. doi:10.1038/s41467-024-47795-3

Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB.

Lampson BL, Ramίrez AS, Baro M, et al. Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB. Cell. 2024;187(9):2209-2223.e16. doi:10.1016/j.cell.2024.03.022

Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice.

Guo B, Liu T, Choi S, et al. Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice. Cell reports. Medicine. 2024:101534. doi:10.1016/j.xcrm.2024.101534

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes.

Chen Z, Guo X, Tao R, et al. Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes. Nature communications. 2024;15(1):3557. doi:10.1038/s41467-024-47399-x

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.

Purdue MP, Dutta D, Machiela MJ, et al. Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nature genetics. 2024. doi:10.1038/s41588-024-01725-7

Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice.

Guo B, Liu T, Choi S, et al. Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice. Cell reports. Medicine. 2024:101534. doi:10.1016/j.xcrm.2024.101534