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Publications

Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries.

Zheng Z, Liu S, Sidorenko J, et al. Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature genetics. 2024. doi:10.1038/s41588-024-01704-y

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, et al. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature genetics. 2024. doi:10.1038/s41588-024-01714-w

Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network.

Lewis ACF, Chisholm RL, Connolly JJ, et al. Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.04.005

Pre-diagnostic plasma proteomics profile for hepatocellular carcinoma.

Zhang X, Zhao L, Ngo LH, et al. Pre-diagnostic plasma proteomics profile for hepatocellular carcinoma. Journal of the National Cancer Institute. 2024. doi:10.1093/jnci/djae079

Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.

Senkpeil L, Bhardwaj J, Little MR, et al. Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine. JCI insight. 2024. doi:10.1172/jci.insight.167408

Experiences of trauma and psychometric properties of the Life Events Checklist among adults in Uganda.

Morawej Z, Misra S, Ametaj AA, et al. Experiences of trauma and psychometric properties of the Life Events Checklist among adults in Uganda. PloS one. 2024;19(4):e0298385. doi:10.1371/journal.pone.0298385

Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings.

Berger AG, DeLorenzo C, Vo C, Kaskow JA, Nabar N, Hammond PT. Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings. Biomacromolecules. 2024. doi:10.1021/acs.biomac.4c00062

High-Throughput, Label-Free Detection of DNA Origami in Single-Cell Suspensions Using origamiFISH-Flow.

Alexander S, Wang WX, Tseng CY, Douglas TR, Chou LYT. High-Throughput, Label-Free Detection of DNA Origami in Single-Cell Suspensions Using origamiFISH-Flow. Small (Weinheim an der Bergstrasse, Germany). 2024:e2400236. doi:10.1002/smll.202400236

An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection.

Ziegler CGK, Owings AH, Galeas-Pena M, et al. An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum. 2024:e0351623. doi:10.1128/spectrum.03516-23

Gut microbiome composition and metabolic activity in women with diverticulitis.

Ma W, Wang Y, Nguyen LH, et al. Gut microbiome composition and metabolic activity in women with diverticulitis. Nature communications. 2024;15(1):3612. doi:10.1038/s41467-024-47859-4