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Publications

The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.

Sumida TS, Cheru NT, Hafler DA. The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases. Nature reviews. Immunology. 2024. doi:10.1038/s41577-024-00994-x

Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.

Lennon NJ, Kottyan LC, Kachulis C, et al. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature medicine. 2024. doi:10.1038/s41591-024-02796-z

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2.

Pérez-Jurado LA, Cáceres A, Balagué-Dobón L, et al. Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2. Communications biology. 2024;7(1):202. doi:10.1038/s42003-024-05805-6

The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.

Venner E, Patterson K, Kalra D, et al. The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities. Communications biology. 2024;7(1):174. doi:10.1038/s42003-023-05708-y

The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities.

Pearson TA, Vitalis D, Pratt C, et al. The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities. JACC. Advances. 2024;3(1). doi:10.1016/j.jacadv.2023.100759

Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2.

He J, Blazeski A, Nilanthi U, et al. Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.01.24.576555

Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge.

Lawson CL, Kryshtafovych A, Pintilie GD, et al. Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Research square. 2024. doi:10.21203/rs.3.rs-3864137/v1

Cell Painting Gallery: an open resource for image-based profiling.

Weisbart E, Kumar A, Arevalo J, Carpenter AE, Cimini BA, Singh S. Cell Painting Gallery: an open resource for image-based profiling. ArXiv. 2024.

Harmonizing the Generation and Pre-publication Stewardship of FAIR Image data.

Bialy N, Alber F, Andrews B, et al. Harmonizing the Generation and Pre-publication Stewardship of FAIR Image data. ArXiv. 2024.

Genome-wide association analysis of composite sleep health scores in 413,904 individuals.

Goodman MO, Faquih T, Paz V, et al. Genome-wide association analysis of composite sleep health scores in 413,904 individuals. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.02.02.24302211