Publications

Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank.

Seal S, Spjuth O, Hosseini-Gerami L, et al. Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.10.15.562398

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.

Ottensmann L, Tabassum R, Ruotsalainen SE, et al. Genome-wide association analysis of plasma lipidome identifies 495 genetic associations. Nature communications. 2023;14(1):6934. doi:10.1038/s41467-023-42532-8

Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.

Sun N, Akay LA, Murdock MH, et al. Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease. Nature neuroscience. 2023;26(12):2251. doi:10.1038/s41593-023-01507-0

Genomic insights into the mechanisms of FGFR1 dependency in squamous cell lung cancer.

Mäkinen N, Meyerson M. Genomic insights into the mechanisms of FGFR1 dependency in squamous cell lung cancer. The Journal of clinical investigation. 2023;133(21). doi:10.1172/JCI174171

Somatic TET2 Mutations are Associated with Giant Cell Arteritis.

Robinette ML, Weeks LD, Kramer RJ, et al. Somatic TET2 Mutations are Associated with Giant Cell Arteritis. Arthritis & rheumatology (Hoboken, N.J.). 2023. doi:10.1002/art.42738

Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis.

Akbar I, Tang R, Baillargeon J, et al. Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). 2023;211(12):1762-1766. doi:10.4049/jimmunol.2300526

Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.

Tao Y, Felber JG, Zou Z, et al. Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2. Angewandte Chemie (International ed. in English). 2023;62(51):e202311924. doi:10.1002/anie.202311924

Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations.

Varkaris A, de la Cruz FF, Martin EE, et al. Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations. Cancer discovery. 2023. doi:10.1158/2159-8290.CD-23-0704

Multiple-instance learning of somatic mutations for the classification of tumour type and the prediction of microsatellite status.

Anaya J, Sidhom JW, Mahmood F, Baras AS. Multiple-instance learning of somatic mutations for the classification of tumour type and the prediction of microsatellite status. Nature biomedical engineering. 2023. doi:10.1038/s41551-023-01120-3

A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain.

Chen CH, Newman LN, Stark AP, et al. A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain. Nature neuroscience. 2023;26(11):1929-1941. doi:10.1038/s41593-023-01462-w

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Publications

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