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Publications

scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution.

Hingerl JC, Martens LD, Karollus A, et al. scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.19.613754

Exome wide association study for blood lipids in 1,158,017 individuals from diverse populations.

Koyama S, Yu Z, Choi SH, et al. Exome wide association study for blood lipids in 1,158,017 individuals from diverse populations. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.09.17.24313718

Calibration of additional computational tools expands ClinGen recommendation options for variant classification with PP3/BP4 criteria.

Bergquist T, Stenton SL, Nadeau EAW, et al. Calibration of additional computational tools expands ClinGen recommendation options for variant classification with PP3/BP4 criteria. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.17.611902

Brain structures with stronger genetic associations are not less associated with family- and state-level economic contexts.

Williams CM, Weissman DG, Mallard TT, McLaughlin KA, Harden P. Brain structures with stronger genetic associations are not less associated with family- and state-level economic contexts. Developmental cognitive neuroscience. 2024;70:101455. doi:10.1016/j.dcn.2024.101455

High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.

Deutsch EW, Kok LW, Mudge JM, et al. High-quality peptide evidence for annotating non-canonical open reading frames as human proteins. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.09.612016

Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC.

Jha A, Hristov B, Wang X, et al. Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.16.613355

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation.

Akbari A, Barton AR, Gazal S, et al. Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.14.613021

Spatial oncology: Translating contextual biology to the clinic.

Gong D, Arbesfeld-Qiu JM, Perrault E, Bae JW, Hwang WL. Spatial oncology: Translating contextual biology to the clinic. Cancer cell. 2024. doi:10.1016/j.ccell.2024.09.001

Pervasive mislocalization of pathogenic coding variants underlying human disorders.

Lacoste J, Haghighi M, Haider S, et al. Pervasive mislocalization of pathogenic coding variants underlying human disorders. Cell. 2024. doi:10.1016/j.cell.2024.09.003

Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa.

Fihn CA, Lembke HK, Gaulin J, et al. Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa. Bioorganic chemistry. 2024;153:107840. doi:10.1016/j.bioorg.2024.107840