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Publications

Assigning functionality to cysteines by base editing of cancer dependency genes.

Li H, Ma T, Remsberg JR, et al. Assigning functionality to cysteines by base editing of cancer dependency genes. Nature chemical biology. 2023. doi:10.1038/s41589-023-01428-w

Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy.

Kabra M, Shahi PK, Wang Y, et al. Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy. The Journal of clinical investigation. 2023;133(19). doi:10.1172/JCI171356

Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity.

Chitraju C, Fischer AW, Ambaw YA, et al. Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity. eLife. 2023;12. doi:10.7554/eLife.88049

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Nyman J, Denize T, Bakouny Z, et al. Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.01.18.524545

Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer.

Hermida-Prado F, Xie Y, Sherman S, et al. Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer. Cancer research. 2023;83(19):3284-3304. doi:10.1158/0008-5472.CAN-23-1711

Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells.

Truex NL, Rondon A, Rössler SL, et al. Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells. ACS central science. 2023;9(9):1835-1845. doi:10.1021/acscentsci.3c00625

CD11a regulates hematopoietic stem and progenitor cells.

Hou L, Yuki K. CD11a regulates hematopoietic stem and progenitor cells. Frontiers in immunology. 2023;14:1219953. doi:10.3389/fimmu.2023.1219953

Periodontal disease is not associated with risk of inflammatory bowel disease: Results from two prospective cohort studies in the US.

Williams KM, Challa PK, Lopes EW, et al. Periodontal disease is not associated with risk of inflammatory bowel disease: Results from two prospective cohort studies in the US. Alimentary pharmacology & therapeutics. 2023. doi:10.1111/apt.17732

Comparison between self-reported and actigraphy-derived sleep measures in patients receiving home parenteral nutrition: Secondary analysis of observational data.

Rahmoune A, Winkler MF, Saxena R, Compher C, Dashti HS. Comparison between self-reported and actigraphy-derived sleep measures in patients receiving home parenteral nutrition: Secondary analysis of observational data. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2023. doi:10.1002/ncp.11077

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty AR, Mullins N, Ashley-Koch AE, et al. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. The American journal of psychiatry. 2023;180(10):723-738. doi:10.1176/appi.ajp.21121266