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Publications

Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders.

Lizano P, Pong S, Santarriaga S, Bannai D, Karmacharya R. Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders. Molecular psychiatry. 2023. doi:10.1038/s41380-023-02255-0

Transgenic ferret models define pulmonary ionocyte diversity and function.

Yuan F, Gasser GN, Lemire E, et al. Transgenic ferret models define pulmonary ionocyte diversity and function. Nature. 2023. doi:10.1038/s41586-023-06549-9

Proteomic architecture of frailty across the spectrum of cardiovascular disease.

Perry AS, Zhao S, Gajjar P, et al. Proteomic architecture of frailty across the spectrum of cardiovascular disease. Aging cell. 2023. doi:10.1111/acel.13978

Single-Cell RNA Sequencing Reveals Cellular Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress.

Salazar-Martín AG, Kalluri AS, Villanueva MA, et al. Single-Cell RNA Sequencing Reveals Cellular Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress. Arteriosclerosis, thrombosis, and vascular biology. 2023. doi:10.1161/ATVBAHA.123.319283

Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses.

Kahraman S, Shibue K, De Jesus DF, et al. Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses. eLife. 2023;12. doi:10.7554/eLife.85056

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Nyman J, Denize T, Bakouny Z, et al. Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. Cell reports. Medicine. 2023;4(9):101189. doi:10.1016/j.xcrm.2023.101189

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review.

Figtree GA, Vernon ST, Harmer JA, et al. Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 2023;82(13):1343-1359. doi:10.1016/j.jacc.2023.06.045

Consumption of Ultraprocessed Food and Risk of Depression.

Samuthpongtorn C, Nguyen LH, Okereke OI, et al. Consumption of Ultraprocessed Food and Risk of Depression. JAMA network open. 2023;6(9):e2334770. doi:10.1001/jamanetworkopen.2023.34770

Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing.

Hacken ET, Gruber M, Hernández-Sánchez M, et al. Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing. STAR protocols. 2023;4(4):102165. doi:10.1016/j.xpro.2023.102165

TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.

Wu G, Yoshida N, Liu J, et al. TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence. Science translational medicine. 2023;15(714):eadi7244. doi:10.1126/scitranslmed.adi7244